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改良式Meso-Rex分流术治疗成人尸体供肝肝移植术后迟发性门静脉海绵样变伴门静脉高压的病例报告

Case report of a modified Meso-Rex bypass as a treatment technique for late-onset portal vein cavernous transformation with portal hypertension after adult deceased-donor liver transplantation.

作者信息

Han Dongdong, Tang Rui, Wang Liang, Li Ang, Huang Xin, Shen Shan, Dong Jiahong

机构信息

Department of Hepatopancreatobiliary Surgery, Medical Center, Tsinghua University, Beijing Tsinghua Changgung Hospital, Beijing, China.

出版信息

Medicine (Baltimore). 2017 Jun;96(25):e7208. doi: 10.1097/MD.0000000000007208.

Abstract

RATIONALE

Portal vein thrombosis is a complication after liver transplantation and cavernous transformation of the portal vein (CTPV) is a result of portal vein thrombosis, with symptoms of portal hypertension revealed by an enhanced CT scan. Meso-Rex bypass is an artificial shunt connecting the left portal vein to the superior mesenteric vein and is mainly used for idiopathic cavernomas. This technique is also used for post-transplant portal vein thrombosis in pediatric patients thereby bypassing obstructed sites of the extrahepatic portal vein. Here we report about an adult patient who was treated by connecting the cystic part of the portal vein to the splenic vein instead of the superior mesenteric vein.

PATIENTS CONCERN

An adult male patient with post-liver transplantation portal vein cavernous transformation suffered from hypersplenism and elevated hepatic enzymes.

DIAGNOSIS

The last follow up revealed irregular and obvious hypersplenism, and splenomegaly had occurred, while an enhanced CT scan revealed serious esophagogastric varices and CTPV in addition to occluded right and common PV trunks.

INTERVENTION

The patient was treated by connecting the cystic part of the portal vein to the splenic vein instead of the superior mesenteric vein.

OUTCOME

After the operation, a satisfactory velocity was confirmed 1 month postoperatively and the shunt still remained patent at the 6-month postoperation follow-up.

LESSONS

A Meso-Rex bypass intervention connecting the left portal vein to the splenic vein instead of the superior mesenteric vein after liver transplantation in an adult patient with right and common portal vein occlusions has been successfully performed as an alternative approach.

摘要

原理

门静脉血栓形成是肝移植后的一种并发症,门静脉海绵样变性(CTPV)是门静脉血栓形成的结果,增强CT扫描可显示门静脉高压症状。肠系膜上静脉-雷克斯分流术是一种将左门静脉与肠系膜上静脉相连的人工分流术,主要用于特发性海绵状血管瘤。该技术也用于小儿患者移植后门静脉血栓形成,从而绕过肝外门静脉阻塞部位。在此,我们报告一例成年患者,其门静脉囊性部分与脾静脉相连而非肠系膜上静脉。

患者情况

一名成年男性患者,肝移植后门静脉海绵样变性,伴有脾功能亢进和肝酶升高。

诊断

最后一次随访显示有不规则且明显的脾功能亢进,已出现脾肿大,增强CT扫描显示除右门静脉主干和门静脉主干闭塞外,还有严重的食管胃静脉曲张和CTPV。

干预措施

该患者接受了门静脉囊性部分与脾静脉相连而非肠系膜上静脉的治疗。

结果

术后1个月确认血流速度良好,术后6个月随访时分流仍保持通畅。

经验教训

在一名右门静脉主干和门静脉主干闭塞的成年患者肝移植后,成功实施了一种替代方法,即肠系膜上静脉-雷克斯分流术,将左门静脉与脾静脉相连而非肠系膜上静脉。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa16/5484218/dd970b886364/medi-96-e7208-g001.jpg

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