Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Department of Neuroscience, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Neuron. 2017 Jun 21;94(6):1043-1046. doi: 10.1016/j.neuron.2017.06.016.
In this issue of Neuron, Welsbie et al. (2017) and Norsworthy et al. (2017) implicate the transcription factor Sox11 as a key player after optic nerve injury-in DLK signaling of RGC cell death, and in RGC regeneration and survival but only in certain RGCs.
本期《神经元》杂志中，Welsbie 等人（2017 年）和 Norsworthy 等人（2017 年）表明，转录因子 Sox11 是视神经损伤后一个关键因子——它在 RGC 细胞死亡的 DLK 信号中发挥作用，在 RGC 再生和存活中也发挥作用，但仅在某些 RGC 中发挥作用。
