Benzaquen M, Marmottant E, Parola P, Berbis P
Service de dermatologie, hôpital Nord, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université, 13015 Marseille, France.
Service de dermatologie, hôpital Nord, Assistance publique-Hôpitaux de Marseille, Aix-Marseille université, 13015 Marseille, France.
Ann Dermatol Venereol. 2017 Oct;144(10):607-611. doi: 10.1016/j.annder.2017.05.006. Epub 2017 Jun 19.
Dirofilariasis is a worldwide zoonotic infection that rarely affects humans and is caused by filarial nematodes of the genus Diroflaria transmitted by mosquitoes. Cutaneous dirofilariasis, due to D. repens, presents as inflammatory lesions that develop into subcutaneous nodules. These clinical symptoms may be consistent with Wells' cellulitis. Diagnosis of dirofilariasis involves demonstration of the presence of the nematode during skin biopsy and identification of the worm through macroscopic, histological and PCR analysis. Surgical resection of the nodule remains the gold standard treatment. The number of cases of human cutaneous dirofilariasis has increased in the recent years and the disease must not be misdiagnosed.
犬恶丝虫病是一种全球性的人畜共患感染病,极少感染人类,由蚊子传播的恶丝虫属丝状线虫引起。由匐行恶丝虫引起的皮肤犬恶丝虫病表现为炎症性病变,可发展为皮下结节。这些临床症状可能与韦尔斯蜂窝织炎一致。犬恶丝虫病的诊断包括在皮肤活检时证明线虫的存在,并通过宏观、组织学和聚合酶链反应分析来鉴定虫体。手术切除结节仍然是金标准治疗方法。近年来,人类皮肤犬恶丝虫病的病例数有所增加,该病不可误诊。