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运动诱发性支气管痉挛与过敏

Exercise-Induced Bronchospasm and Allergy.

作者信息

Caggiano Serena, Cutrera Renato, Di Marco Antonio, Turchetta Attilio

机构信息

Respiratory Intermediate Care Unit, Pediatric Department, Bambino Gesù Children's Hospital, Rome, Italy.

Sleep and Long Term Ventilation Unit, Pediatric Department, Bambino Gesù Children's Hospital, Rome, Italy.

出版信息

Front Pediatr. 2017 Jun 8;5:131. doi: 10.3389/fped.2017.00131. eCollection 2017.

Abstract

Sport is an essential part of childhood, with precious and acknowledged positive health effects but the impact of exercise-induced bronchoconstriction (EIB) significantly reduces participation in physical activity. It is important to recognize EIB, differentiating EIB with or without asthma if the transient narrowing of the airways after exercise is associated with asthmatic symptoms or not, in the way to select the most appropriate treatment among the many treatment options available today. Therapy is prescribed based on symptoms severity but diagnosis of EIB is established by changes in lung function provoked by exercise evaluating by direct and indirect tests. Sometimes, in younger children it is difficult to obtain the registration of difference between the preexercise forced expiratory volume in the first second (FEV1) value and the lowest FEV1 value recorded within 30 min after exercise, defined as the gold standard, but interrupter resistance, in association with spirometry, has been showed to be a valid alternative in preschool age. Atopy is the main risk factor, as demonstrated by epidemiologic data showing that among the estimated pediatric population with EIB up to 40% of them have allergic rhinitis and 30% of these patients may develop adult asthma, according with atopic march. Adopting the right treatment and prevention, selecting sports with no marked hyperventilation and excessive cooling of the airways, children with EIB can be able to take part in physical activity like all others.

摘要

运动是童年的重要组成部分,具有宝贵且公认的积极健康影响,但运动诱发的支气管收缩(EIB)的影响会显著降低体育活动的参与度。认识到EIB很重要,如果运动后气道的短暂狭窄是否与哮喘症状相关,要区分有或没有哮喘的EIB,以便在当今众多可用的治疗选择中选择最合适的治疗方法。治疗是根据症状严重程度开处方的,但EIB的诊断是通过运动诱发的肺功能变化来确定的,通过直接和间接测试进行评估。有时,对于年幼儿童来说,很难获得运动前第一秒用力呼气量(FEV1)值与运动后30分钟内记录的最低FEV1值之间差异的记录,这被定义为金标准,但在学龄前儿童中,与肺活量测定法相关的阻断阻力已被证明是一种有效的替代方法。特应性是主要危险因素,流行病学数据表明,在估计患有EIB的儿科人群中,高达40%的人患有过敏性鼻炎,其中30%的患者可能会发展为成人哮喘,这与特应性进程相符。通过采取正确的治疗和预防措施,选择没有明显过度通气和气道过度冷却的运动,患有EIB的儿童能够像其他儿童一样参加体育活动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2496/5462910/82c7f70c7840/fped-05-00131-g001.jpg

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