Sharma Deepti, Singh Garima
Department of Radiation Oncology, VMMC and Safdarjung Hospital, New Delhi, India.
J Cancer Res Ther. 2017 Apr-Jun;13(2):193-197. doi: 10.4103/0973-1482.189234.
Thrombocytosis has been suggested to be a poor prognostic indicator in malignancies. Studies have shown that thrombocytosis is associated with a poor prognosis in various gynecological malignancies such as carcinoma ovary, cervical cancer, and endometrial cancer. The aim of this study is to analyze the impact of thrombocytosis on the prognosis of gynecological cancer. All the relevant data were retrieved by PubMed, MEDLINE, and Web of Science, and then studies were chosen in this analysis of association between thrombocytosis and gynecological malignancy. Thrombocytosis is common in advanced disease in patients with ovarian cancer, endometrial cancer, and cervical cancer. Therefore, it may be a marker of tumor burden or biologically more aggressive disease. Thrombocytosis is bad prognostic factor and associated with poorer outcomes.
血小板增多症被认为是恶性肿瘤预后不良的指标。研究表明,血小板增多症与多种妇科恶性肿瘤(如卵巢癌、宫颈癌和子宫内膜癌)的预后不良有关。本研究的目的是分析血小板增多症对妇科癌症预后的影响。所有相关数据通过PubMed、MEDLINE和科学网检索,然后选择这些研究来分析血小板增多症与妇科恶性肿瘤之间的关联。血小板增多症在卵巢癌、子宫内膜癌和宫颈癌患者的晚期疾病中很常见。因此,它可能是肿瘤负荷或生物学上更具侵袭性疾病的标志物。血小板增多症是不良预后因素,与较差的结局相关。