埃塞俄比亚农村医院 16 年以上收治的儿童和青少年麻风流行病学和临床特征：回顾性分析。

Epidemiological and Clinical Characteristics of Children and Adolescents with Leprosy Admitted Over 16 Years at a Rural Hospital in Ethiopia: A Retrospective Analysis.

机构信息

Department of Paediatrics and Medicine, Gambo Rural General Hospital, Shashemane, Ethiopia.

Department of Internal Medicine, Hospital General Universitario de Alicante, Alicante 03010, Spain.

出版信息

J Trop Pediatr. 2018 Jun 1;64(3):195-201. doi: 10.1093/tropej/fmx048.

DOI:10.1093/tropej/fmx048

PMID:28645166

Abstract

AIM

To analyse differences in children and adolescents aged ≤18 years admitted to the leprosy ward in a rural Ethiopian hospital >16 years.

METHODS

We retrospectively collected data from leprosy admission registry books on patients with leprosy who were admitted to a referral hospital from September 2000 to September 2016.

RESULTS

There were 2129 admissions for leprosy during the study period: 180 (8.4%) patients were s ≤ 18 years old. Of these, 98 (54.4%) were male and 82 (45.6%) were female. The proportion of new diagnoses in children and adolescents was 31.7%, significantly higher than in adults (11.7%; p < 0.001). There were also significant differences in the prevalence of lepromatous ulcers (46.9 vs. 61.7%), leprosy reaction (29.4 vs. 13.0%) and neuritis (16.9 vs.5.3%) between these age groups.

CONCLUSIONS

There were more new diagnoses, leprosy reactions and neuritis, and fewer lepromatous ulcers, in children and adolescents compared with adults, with younger patients being referred more frequently to reference centres.

摘要

目的

分析在埃塞俄比亚农村医院麻风病房中，16 岁以上≤18 岁的儿童和青少年患者的差异。

方法

我们回顾性地从 2000 年 9 月至 2016 年 9 月间转诊至一家专科医院的麻风病入院登记册中收集麻风病患者的数据。

结果

在研究期间，共有 2129 例麻风病住院患者：180 例（8.4%）患者年龄≤18 岁。其中，98 例（54.4%）为男性，82 例（45.6%）为女性。儿童和青少年中新诊断的比例为 31.7%，显著高于成年人（11.7%；p<0.001）。在儿童和青少年中，瘤型溃疡（46.9%比 61.7%）、麻风反应（29.4%比 13.0%）和神经炎（16.9%比 5.3%）的比例也存在显著差异。