Pace Collier S, Merritt Wyndell H
1 Virginia Commonwealth University, Richmond, USA.
Hand (N Y). 2018 Jul;13(4):395-402. doi: 10.1177/1558944717715119. Epub 2017 Jun 23.
Periarterial sympathectomy is a proposed surgical treatment for patients with refractory Raynaud syndrome; however, there is debate regarding the indications and extent of dissection. Due to the segmental arterial sympathetic innervation, we favor an extended sympathectomy in concert with vein graft reconstruction of occluded vessels when necessary. The purpose of this study is to examine outcomes of extended periarterial sympathectomy in our patients.
A retrospective chart review was performed on 46 patients who underwent 58 periarterial sympathectomies (12 bilateral) since 1981. The data collected include demographics, comorbidities, previous therapy, operative details, and surgical outcomes. In addition, we contacted available patients for a phone survey.
Of 58 cases, 68.9% were female, 29.3% were current smokers, and 58.6% had known connective tissue disease. Thirty-three vein graft reconstructions were performed with a long-term patency of 77.4%. Sustained improvement of ischemic pain was reported in 94.8% of cases, and 78% of patients with ulcers completely healed. For the most symptomatic fingertip, mean Semmes-Weinstein monofilament measurements improved from 4.15 preoperatively to 3.29 postoperatively ( P ≤ .05). Mean follow-up was 3.97 years. Of 10 patients contacted by telephone, all reported a decrease in frequency and severity of Raynaud attacks, while 9 reported a long-term decrease in pain an average of 11.6 years after surgery.
Extended periarterial sympathectomy is an effective and safe procedure for patients with refractory Raynaud syndrome. Our data demonstrate long-term improvement in ischemic pain and sensibility, along with a high rate of ulcer healing and patient satisfaction.
动脉周围交感神经切除术是一种针对难治性雷诺综合征患者提出的外科治疗方法;然而,关于手术适应症和解剖范围仍存在争议。由于动脉交感神经呈节段性分布,我们倾向于在必要时进行扩大交感神经切除术,并同时对闭塞血管进行静脉移植重建。本研究的目的是探讨扩大动脉周围交感神经切除术在我们患者中的治疗效果。
对1981年以来接受58例动脉周围交感神经切除术(12例双侧手术)的46例患者进行回顾性病历分析。收集的数据包括人口统计学资料、合并症、既往治疗情况、手术细节和手术结果。此外,我们还联系了可联系到的患者进行电话调查。
在58例病例中,68.9%为女性,29.3%为现吸烟者,58.6%患有已知的结缔组织病。进行了33例静脉移植重建,长期通畅率为77.4%。94.8%的病例报告缺血性疼痛持续改善,78%的溃疡患者完全愈合。对于症状最明显的指尖,平均Semmes-Weinstein单丝测量值从术前的4.15改善至术后的3.29(P≤0.05)。平均随访时间为3.97年。在通过电话联系的10例患者中,所有患者均报告雷诺发作的频率和严重程度降低,9例患者报告术后平均11.6年疼痛长期减轻。
扩大动脉周围交感神经切除术对于难治性雷诺综合征患者是一种有效且安全的手术方法。我们的数据表明,缺血性疼痛和感觉功能得到长期改善,溃疡愈合率高,患者满意度高。