The Ohio State University Wexner Medical Center, Columbus, USA.
Hand (N Y). 2023 Jan;18(1):32-39. doi: 10.1177/15589447211017211. Epub 2021 May 31.
Systemic sclerosis (scleroderma, SSc) is an autoimmune disease that causes significant dysfunction to multiple organ systems, including the musculoskeletal system. It poses significant challenges to the hand surgeon, including calcinosis, ischemic changes, Raynaud phenomenon, tendinopathies, synovitis, and joint contractures. Patients with SSc also suffer from multiorgan dysfunction, which makes them high-risk surgical patients. The hand surgeon must understand the pathophysiology, treatment strategies, and special operative considerations required in this population to avoid complications and help maintain or improve hand function.
系统性硬化症（硬皮病，SSc）是一种自身免疫性疾病，可导致包括肌肉骨骼系统在内的多个器官系统功能显著障碍。它给手外科医生带来了重大挑战，包括钙沉积、缺血性改变、雷诺现象、肌腱病、滑膜炎和关节挛缩。SSc 患者还患有多器官功能障碍，这使他们成为高风险手术患者。手外科医生必须了解该人群所需的病理生理学、治疗策略和特殊手术注意事项，以避免并发症并帮助维持或改善手部功能。
