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经皮治疗三尖瓣疾病:“被遗忘”瓣膜的新希望。

Percutaneous Treatment of the Tricuspid Valve Disease: New Hope for the "Forgotten" Valve.

作者信息

Campelo-Parada Francisco, Lairez Olivier, Carrié Didier

机构信息

Department of Cardiology, Rangueil University Hospital, CHU Toulouse, Toulouse, France.

Department of Cardiology, Rangueil University Hospital, CHU Toulouse, Toulouse, France.

出版信息

Rev Esp Cardiol (Engl Ed). 2017 Oct;70(10):856-866. doi: 10.1016/j.rec.2017.05.010. Epub 2017 Jun 20.

Abstract

Tricuspid valve disease is a frequent condition but is currently undertreated. A limited number of patients undergo an isolated surgical tricuspid repair, and this intervention is associated with poor outcomes, especially in patients with previous cardiac surgery. Most patients are only medically treated, despite the impact of severe tricuspid regurgitation on functional status and long-term survival. Transcatheter therapies represent a promising alternative for patients with severe tricuspid regurgitation and high surgical risk. In the last few years, several percutaneous alternatives have been developed for the treatment of functional tricuspid regurgitation. Imaging techniques play an indispensable role in patient selection, procedural guidance and follow-up. The current available transcatheter options for native tricuspid valve disease can be divided into 3 main groups: heterotopic caval valve implantation, annuloplasty devices, and coaptation devices. In patients with previous tricuspid valve surgery, transcatheter valve-in-valve and valve-in-ring procedures have been reported. This review provides a detailed analysis of the novel transcatheter alternatives for the treatment of tricuspid valve disease that have already been successfully implanted in humans, as well as the most important aspects of tricuspid valve anatomy and imaging assessment.

摘要

三尖瓣疾病是一种常见病症,但目前治疗不足。仅有少数患者接受单纯的三尖瓣手术修复,且这种干预措施的预后较差,尤其是在曾接受心脏手术的患者中。尽管严重三尖瓣反流会对功能状态和长期生存产生影响,但大多数患者仅接受药物治疗。经导管治疗对于严重三尖瓣反流且手术风险高的患者而言是一种有前景的替代方案。在过去几年中,已开发出多种经皮治疗方法用于功能性三尖瓣反流的治疗。成像技术在患者选择、手术指导和随访中发挥着不可或缺的作用。目前用于原发性三尖瓣疾病的经导管治疗选择可分为三大类:异位腔静脉瓣植入、瓣环成形装置和瓣叶对合装置。对于曾接受三尖瓣手术的患者,已报道了经导管瓣中瓣和瓣中环手术。本综述详细分析了已成功应用于人体的用于治疗三尖瓣疾病的新型经导管替代方案,以及三尖瓣解剖结构和成像评估的最重要方面。

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