Leem Jungtae, Lee Seunghoon, Park Yeoncheol, Seo Byung-Kwan, Cho Yeeun, Kang Jung Won, Lee Yoon Jae, Ha In-Hyuk, Lee Hyun-Jong, Kim Eun-Jung, Lee Sanghoon, Nam Dongwoo
Department of Clinical Korean Medicine, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea.
Korean Medicine Clinical Trial Center, Kyung Hee University Korean Medicine Hospital, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, South Korea.
BMJ Open. 2017 Jun 23;7(6):e014936. doi: 10.1136/bmjopen-2016-014936.
Many patients experience acute lower back pain that becomes chronic pain. The proportion of patients using complementary and alternative medicine to treat lower back is increasing. Even though several moxibustion clinical trials for lower back pain have been conducted, the effectiveness and safety of moxibustion intervention is controversial. The purpose of this study protocol for a systematic review is to evaluate the effectiveness and safety of moxibustion treatment for non-specific lower back pain patients.
We will conduct an electronic search of several databases from their inception to May 2017, including Embase, PubMed, Cochrane Central Register of Controlled Trial, Allied and Complementary Medicine Database, Wanfang Database, Chongqing VIP Chinese Science and Technology Periodical Database, China National Knowledge Infrastructure Database, Korean Medical Database, Korean Studies Information Service System, National Discovery for Science Leaders, Oriental Medicine Advanced Searching Integrated System, the Korea Institute of Science and Technology, and KoreaMed. Randomised controlled trials investigating any type of moxibustion treatment will be included. The primary outcome will be pain intensity and functional status/disability due to lower back pain. The secondary outcome will be a global measurement of recovery or improvement, work-related outcomes, radiographic improvement of structure, quality of life, and adverse events (presence or absence). Risk ratio or mean differences with a 95% confidence interval will be used to show the effect of moxibustion therapy when it is possible to conduct a meta-analysis.
This review will be published in a peer-reviewed journal and will be presented at an international academic conference for dissemination. Our results will provide current evidence of the effectiveness and safety of moxibustion treatment in non-specific lower back pain patients, and thus will be beneficial to patients, practitioners, and policymakers.
CRD42016047468 in PROSPERO 2016.
许多患者经历急性下背痛后会发展为慢性疼痛。使用补充和替代医学治疗下背痛的患者比例正在增加。尽管已经进行了多项针对下背痛的艾灸临床试验，但艾灸干预的有效性和安全性仍存在争议。本系统评价研究方案的目的是评估艾灸治疗非特异性下背痛患者的有效性和安全性。
我们将对多个数据库进行电子检索，检索时间从建库至2017年5月，包括Embase、PubMed、Cochrane对照试验中心注册库、补充与替代医学数据库、万方数据库、重庆维普中文科技期刊数据库、中国知网数据库、韩国医学数据库、韩国研究信息服务系统、国家科学领袖发现数据库、东方医学高级检索集成系统、韩国科学技术院以及KoreaMed。纳入任何类型艾灸治疗的随机对照试验。主要结局将是下背痛导致的疼痛强度和功能状态/残疾情况。次要结局将是恢复或改善的整体评估、与工作相关的结局、结构的影像学改善、生活质量以及不良事件（有无）。当有可能进行荟萃分析时，将使用风险比或95%置信区间的均值差异来显示艾灸疗法的效果。
本综述将发表在同行评审期刊上，并将在国际学术会议上进行展示以传播。我们的结果将提供艾灸治疗非特异性下背痛患者有效性和安全性的当前证据，因此将对患者、从业者和政策制定者有益。
PROSPERO 2016中的CRD42016047468
