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大鼠弓状核神经元中生长激素释放因子样免疫反应性与酪氨酸羟化酶样免疫反应性的共存。

Coexistence of growth hormone releasing factor-like and tyrosine hydroxylase-like immunoreactivities in neurons of the rat arcuate nucleus.

作者信息

Okamura H, Murakami S, Chihara K, Nagatsu I, Ibata Y

出版信息

Neuroendocrinology. 1985 Aug;41(2):177-9. doi: 10.1159/000124172.

DOI:10.1159/000124172
PMID:2864650
Abstract

Neurons synthesizing growth hormone releasing factor were detected by immunocytochemistry with specific antiserum against synthetic rat hypothalamic growth hormone releasing factor. Growth hormone releasing factor immunoreactive neurons which also showed tyrosine hydroxylase immunoreactivity were located in the ventrolateral part of the arcuate nucleus. The functional significance of this finding for anterior pituitary hormone secretion is discussed.

摘要

用针对合成大鼠下丘脑生长激素释放因子的特异性抗血清，通过免疫细胞化学方法检测合成生长激素释放因子的神经元。同时显示酪氨酸羟化酶免疫反应性的生长激素释放因子免疫反应性神经元位于弓状核的腹外侧部分。讨论了这一发现对垂体前叶激素分泌的功能意义。

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