苏丹患先兆子痫女性的母血抗苗勒管激素
Maternal serum anti-Müllerian hormone in Sudanese women with preeclampsia.
作者信息
Agabain Eiman, Mohamed Hameed, Elsheikh Anas E, Hamdan Hamdan Z, Adam Ishag
机构信息
Medical College, Qassim University, Buraydah, Kingdom of Saudi Arabia.
Faculty of Medicine, Alneelain University, Khartoum, Sudan.
出版信息
BMC Res Notes. 2017 Jun 24;10(1):217. doi: 10.1186/s13104-017-2544-6.
OBJECTIVES
A case-control study was conducted at Omdurman Maternity Tertiary Hospital, Sudan, during the period from May to August 2014 to investigate AMH level in women with preeclampsia compared to healthy controls. The cases were women with preeclampsia and healthy pregnant women were the controls. The obstetrics and medical history was gathered using a questionnaire. AMH level was measured using ELISA.
RESULTS
There was no significant difference between the two groups (40 in each arm of the study) in the age, parity and gestational age. Thirty-three of the 40 cases were patients with severe preeclampsia. There was no significant difference in median inter-quartile of the AMH level between the women with preeclampsia and the controls [0.700 (0.225-1.500) vs. 0.700 (0.400-1.275) ng/ml, P = 0.967]. In a linear regression model there was no association between the log of AMH and age, parity, gestational age, BMI, hemoglobin level and preeclampsia.
目的
2014年5月至8月期间，在苏丹恩图曼妇产三级医院开展了一项病例对照研究，以调查子痫前期女性与健康对照者的抗缪勒管激素（AMH）水平。病例为子痫前期女性，健康孕妇为对照。通过问卷收集产科和病史。使用酶联免疫吸附测定法（ELISA）测量AMH水平。
结果
两组（研究每组各40例）在年龄、产次和孕周方面无显著差异。40例病例中有33例为重度子痫前期患者。子痫前期女性与对照者之间AMH水平的中位数四分位数间距无显著差异[0.700（0.225 - 1.500）对0.700（0.400 - 1.275）ng/ml，P = 0.967]。在一个线性回归模型中，AMH的对数与年龄、产次、孕周、体重指数、血红蛋白水平和子痫前期之间无关联。
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