Klinikum Coburg, Coburg, Germany.
Denver Nephrology, Denver, Colorado, USA.
Kidney Int. 2017 Jul;92(1):26-36. doi: 10.1016/j.kint.2017.04.006.
The KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of CKD-MBD represents a selective update of the prior CKD-MBD Guideline published in 2009. This update, along with the 2009 publication, is intended to assist the practitioner caring for adults and children with chronic kidney disease (CKD), those on chronic dialysis therapy, or individuals with a kidney transplant. This review highlights key aspects of the 2017 CKD-MBD Guideline Update, with an emphasis on the rationale for the changes made to the original guideline document. Topic areas encompassing updated recommendations include diagnosis of bone abnormalities in CKD-mineral and bone disorder (MBD), treatment of CKD-MBD by targeting phosphate lowering and calcium maintenance, treatment of abnormalities in parathyroid hormone in CKD-MBD, treatment of bone abnormalities by antiresorptives and other osteoporosis therapies, and evaluation and treatment of kidney transplant bone disease.
KDIGO 2017 年慢性肾脏病矿物质和骨异常诊治临床实践指南更新版代表了 2009 年发布的慢性肾脏病矿物质和骨异常指南的选择性更新。本更新版与 2009 年的出版物旨在为慢性肾脏病（CKD）的成人和儿童、慢性透析治疗的患者或肾移植患者的医护人员提供帮助。本综述重点介绍了 2017 年慢性肾脏病矿物质和骨异常指南更新版的关键方面，并强调了对原始指南文件所做更改的基本原理。涵盖更新建议的主题领域包括 CKD 矿物质和骨异常中骨异常的诊断、通过降低磷酸盐和维持钙来治疗 CKD-MBD、CKD-MBD 中甲状旁腺激素异常的治疗、通过抗吸收剂和其他骨质疏松症治疗来治疗骨异常，以及肾移植骨病的评估和治疗。
