Lasek R, Müller M
Psychiatr Neurol Med Psychol (Leipz). 1985 Jul;37(7):385-99.
The paper provides a survey of neuropharmacological fundamentals for the use of beta-adrenolytics in the treatment of psychiatric and neurological diseases. In particular there are discussed results of animal- and clinical-pharmacological experiments carried out in order to assess the influence of betaadrenolytics in disorders and diseases such as anxiety, psychoses, tremor, some kinds of addiction, migraine and epilepsy. The conclusion is that in spite of some ascertained clinical indications on the one hand and a variety of neuropharmacological results on the other the mode of action of betaadrenolytics at the level of the CNS remains still insufficiently explainable.
本文综述了β-肾上腺素能阻滞剂用于治疗精神和神经疾病的神经药理学基础。特别讨论了为评估β-肾上腺素能阻滞剂对焦虑、精神病、震颤、某些成瘾、偏头痛和癫痫等病症和疾病的影响而进行的动物和临床药理学实验结果。结论是，一方面尽管有一些已确定的临床适应症，另一方面有各种各样的神经药理学结果，但β-肾上腺素能阻滞剂在中枢神经系统水平的作用方式仍难以充分解释。
