Salam Sharfaraz, Anandarajah Mayooreshan, Al-Bachari Sarah, Pal Piyali, Sussman Jonathan, Hamdalla Hisham
Department of Neurology, Greater Manchester Neurosciences Centre, Salford Royal NHS Trust, Salford, UK.
Royal Preston Hospital, Preston, UK.
Pract Neurol. 2017 Oct;17(5):392-395. doi: 10.1136/practneurol-2017-001599. Epub 2017 Jun 24.
Cerebral amyloid angiopathy-related inflammation (CAA-I) is a rare variant of cerebral amyloid angiopathy (CAA). Its precise pathophysiology remains uncertain and we currently have limited evidence on which immunosuppressive agents are the most effective in its treatment. The disease course of CAA-I disorders can vary from an isolated clinical event to recurrent episodes. We present a case of biopsy-confirmed CAA-I that gives insight into its potential relapsing nature and the challenges of its long-term management.
脑淀粉样血管病相关炎症（CAA-I）是脑淀粉样血管病（CAA）的一种罕见变体。其确切的病理生理学仍不确定，目前我们对于哪种免疫抑制剂在其治疗中最有效仅有有限的证据。CAA-I疾病的病程可能从孤立的临床事件到反复发作不等。我们报告一例经活检证实的CAA-I病例，该病例有助于深入了解其潜在的复发性本质及其长期管理的挑战。
