Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
J Refract Surg. 2013 May;29(5):320-4. doi: 10.3928/1081597X-20130415-03.
To evaluate and compare the thickness and the morphology of femtosecond and mechanical microkeratome LASIK flaps using anterior segment optical coherence tomography (AS-OCT).
Bilateral LASIK was performed in 132 eyes from 61 myopic patients. Flaps were created in 72 eyes using the WaveLight FS200 femtosecond laser (Wave-Light GmbH, Erlangen, Germany) and in 50 eyes using the Moria microkeratome (Moria SA, Antony, France). AS-OCT was used 1 week postoperatively to evaluate the thickness of 17 points across each flap, which were 0, 2, and 3.5 mm to the corneal vertex on the horizontal, vertical, 45°, and 135° meridians.
The mean central flap thickness was 105.53 ± 5.86 μm in the WaveLight group and 132.96 ± 13.91 μm in the Moria group (P < .001). The difference between the achieved and the intended flap thickness (accuracy) was 6.17 ± 3.98 and 23.60 ± 12.64 μm, respectively (P < .001). The standard deviation within individual flap (uniformity) was smaller in the WaveLight group. The symmetry and regularity were also better in the WaveLight group. Flap morphology showed a more regular planar shape in the WaveLight group and a meniscus shape in the Moria group.
AS-OCT showed that the flaps created by the WaveLight femtosecond laser were more accurate, reproducible, and uniform than those created by the Moria microkeratome.
使用眼前节光学相干断层扫描(AS-OCT)评估并比较飞秒和机械微型角膜刀 LASIK 瓣的厚度和形态。
对 61 例近视患者的 132 只眼进行双侧 LASIK。72 只眼采用 WaveLight FS200 飞秒激光(德国 Erlangen 的 Wave-Light GmbH)制作角膜瓣,50 只眼采用 Moria 微型角膜刀(法国 Antony 的 Moria SA)制作角膜瓣。术后 1 周,使用 AS-OCT 评估每条角膜瓣的 17 个点的厚度,水平、垂直、45°和 135°子午线距角膜顶点 0、2 和 3.5mm 处。
WaveLight 组的平均中央角膜瓣厚度为 105.53 ± 5.86μm,Moria 组为 132.96 ± 13.91μm(P<0.001)。实际和预期角膜瓣厚度之间的差异(准确性)分别为 6.17 ± 3.98μm 和 23.60 ± 12.64μm(P<0.001)。单个角膜瓣内的标准偏差(均匀性)在 WaveLight 组中较小。WaveLight 组的对称性和规则性也更好。角膜瓣形态显示,WaveLight 组的角膜瓣更规则,呈平面状,而 Moria 组的角膜瓣呈新月形。
AS-OCT 显示,WaveLight 飞秒激光制作的角膜瓣比 Moria 微型角膜刀制作的角膜瓣更精确、可重复且均匀。