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Inhibition of [3H] glutamate release from rat hippocampal slices by L-phenylisopropyladenosine.

作者信息

Fastbom J, Fredholm B B

出版信息

Acta Physiol Scand. 1985 Sep;125(1):121-3. doi: 10.1111/j.1748-1716.1985.tb07698.x.

Abstract

Hippocampal slices were labelled with [3H]glutamate. Evoked release, which was calcium-dependent and inhibited by tetrodotoxin, could be reduced concentration-dependently by L-PIA. The effect of L-PIA was blocked by 10 microM 8-phenyltheophylline. The results indicate that there are adenosine receptors modulating the efflux of glutamate in field stimulated hippocampal slices.

摘要

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