Lü R, Yu C L, Li J, Wen D D, Zheng M W
Department of Radiology, Third Central Hospital of Tianjin; Tianjin Institute of Hepatobiliary Disease; Tianjin Key Laboratory of Artificial Cell; Artificial Cell Engineering Technology Research of Public Health Ministry, Tianjin 300170, China.
Zhonghua Yi Xue Za Zhi. 2017 Jun 20;97(23):1796-1800. doi: 10.3760/cma.j.issn.0376-2491.2017.23.008.
To explore the CT findings of the Takayasu's arteritis (TA)with pulmonary artery (PA) involvement and its clinical significance. A total of 35 patients with TA involving the PA in Xijing Hospital from November 2007 to November 2016, 6 male cases, 29 female cases, the age was 15-52 (28±9) years old, were retrospectively collected and included in the study group (TA+ P group), meanwhile 40 patients with TA but not involving the pulmonary artery in this hospital from January 2015 to November 2016 were collected as control group, 5 male cases, 35 female cases, the age was 7-67 (28±12) years old.The clinical and laboratory data, the pulmonary artery and right heart measurement data of the two groups were compared by using test, χ(2) test , and rank sum test.The CT signs of pulmonary artery involvement in the TA+ P group were analyzed. TA+ P group patients had shortness of breath, wheezing(54.3% vs 10.0%), cough(31.4% vs 12.5%)and palpitations(11.4% vs 0)mostly, and there were statistical difference between TA+ P group and TA group (all <0.05), However, there was no difference between the two groups in the activity and duration of disease (all >0.05). In TA+ P group, a total of 312 pulmonary artery segments were involved in 35 patients.The lumen stenosis of PA was more common(35 cases, 211 segments), followed by occlusion(14 cases, 94 segments), bilateral PA (23 cases, 217 segments) and multiple branches of PA involvement(34 cases, 311 segments) were more common.The PA systolic pressure, the diameter of main pulmonary artery, right atrium and right ventricular width of the TA+ P group patients were significantly higher than those of the TA group (all <0.05). There are some CT certain characteristics in TA pulmonary arterial involvement, and they are not related to the activity and duration of the disease.Most patients with PA involvement present pulmonary hypertension and a series of special clinical manifestations.
探讨累及肺动脉（PA）的大动脉炎（TA）的CT表现及其临床意义。回顾性收集2007年11月至2016年11月在西京医院就诊的35例累及PA的TA患者，其中男性6例，女性29例，年龄15 - 52（28±9）岁，纳入研究组（TA + P组）；同时收集2015年1月至2016年11月在本院就诊的40例未累及肺动脉的TA患者作为对照组，其中男性5例，女性35例，年龄7 - 67（28±12）岁。采用t检验、χ²检验和秩和检验比较两组的临床及实验室资料、肺动脉及右心测量数据。分析TA + P组肺动脉受累的CT征象。TA + P组患者主要表现为气短、喘息（54.3% vs 10.0%）、咳嗽（31.4% vs 12.5%）和心悸（11.4% vs 0），与TA组比较差异均有统计学意义（均P<0.05），但两组疾病活动度及病程差异无统计学意义（均P>0.05）。TA + P组35例患者共累及312个肺动脉节段。PA管腔狭窄较为常见（35例，211个节段），其次为闭塞（共14例，94个节段），双侧PA受累（23例，217个节段）及PA多支受累（34例，311个节段）较为常见。TA + P组患者PA收缩压、主肺动脉内径、右心房及右心室宽度均显著高于TA组（均P<0.05）。TA累及肺动脉有一定的CT特征，且与疾病活动度及病程无关。多数PA受累患者出现肺动脉高压及一系列特殊临床表现。
