Bharani Vani, Ramesh V, Rao Ram Nawal, Tewari Satyendra
Dept. of Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Dept. of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Indian Heart J. 2017 May-Jun;69(3):325-327. doi: 10.1016/j.ihj.2017.03.010. Epub 2017 Mar 25.
Gamma glutamyl transferase (GGT) is emerging as a promising marker for assessing cardiovascular risk. GGT predicts cardiovascular mortality in the population and is positively associated with traditional risk factors for coronary artery disease (CAD). This study was undertaken on 200 north Indian CAD patients diagnosed with coronary angiography to study relation of GGT with risk factors for CAD and severity of CAD. GGT values ranged from 5 to 69U/L and were divided in 4 quartiles. GGT was positively associated with triglyceride (p=0.008) and VLDL cholesterol (p=0.002) in our subjects. Also an increase in total cholesterol from GGT quartile I to quartile IV (p=0.28) was noted.
γ-谷氨酰转移酶（GGT）正逐渐成为评估心血管风险的一个有前景的标志物。GGT可预测人群中的心血管死亡率，并且与冠状动脉疾病（CAD）的传统危险因素呈正相关。本研究对200例经冠状动脉造影诊断为CAD的北印度患者进行，以研究GGT与CAD危险因素及CAD严重程度之间的关系。GGT值范围为5至69U/L，并分为4个四分位数。在我们的研究对象中，GGT与甘油三酯（p = 0.008）和极低密度脂蛋白胆固醇（p = 0.002）呈正相关。此外，还注意到从GGT四分位数I到四分位数IV总胆固醇有所增加（p = 0.28）。
