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肺动脉瘤手术修复的结果:38例患者的单中心经验

Outcome of Surgical Repair of Pulmonary Artery Aneurysms: A Single-Center Experience With 38 Patients.

作者信息

Reisenauer Janani S, Said Sameh M, Schaff Hartzell V, Connolly Heidi M, Maleszewski Joseph J, Dearani Joseph A

机构信息

Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.

Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.

出版信息

Ann Thorac Surg. 2017 Nov;104(5):1605-1610. doi: 10.1016/j.athoracsur.2017.03.077. Epub 2017 Jun 23.

Abstract

BACKGROUND

Pulmonary artery (PA) aneurysms are rare and have been reported only in case reports or small series. We reviewed our experience with surgical repair of PA aneurysms.

METHODS

We reviewed all patients with a true PA aneurysm undergoing cardiac operations between 1995 and 2015. We excluded aneurysms and pseudoaneurysms related to right ventricular outflow tract patches or previous conduits.

RESULTS

There were 38 patients (24 women [63%]; mean age, 46 ± 15 years), and 14 patients (37%) were asymptomatic. The main PA was involved 35 patients (92%). The mean aneurysm diameter was 5.8 ± 1.8 cm. The most common associated pathology was pulmonary valve stenosis/regurgitation in 23 patients (64%). High-pressure (right ventricular systolic pressure >35 mm Hg) aneurysms were present in 23 patients. Operative strategies included reduction arterioplasty in 30 patients (79%) and resection with graft interposition in 8 (21%). The average length of stay was 6.0 ± 2.2 days. There were no early deaths. Late deaths occurred in 3 patients (8%) and were noncardiac related. Late reoperations occurred in 8% and were not related to the PA aneurysm. All high-pressure aneurysms and those larger than 8 cm demonstrated advanced medial necrosis on pathologic examination of the specimens.

CONCLUSIONS

PA aneurysms are a real entity, and surgical repair can be done with low morbidity and mortality. Aneurysmorrhaphy or aneurysmectomy can be performed, depending on the anatomic location. Regardless of the size of the PA, we recommend intervention on high-pressure aneurysms due to the occurrence of advanced medial necrosis.

摘要

背景

肺动脉(PA)瘤罕见,仅在病例报告或小系列研究中有报道。我们回顾了我们在PA瘤手术修复方面的经验。

方法

我们回顾了1995年至2015年间所有接受心脏手术的真性PA瘤患者。我们排除了与右心室流出道补片或既往管道相关的动脉瘤和假性动脉瘤。

结果

共有38例患者(24例女性[63%];平均年龄46±15岁),14例患者(37%)无症状。35例患者(92%)累及主肺动脉。动脉瘤平均直径为5.8±1.8 cm。最常见的相关病变是23例患者(64%)存在肺动脉瓣狭窄/反流。23例患者存在高压(右心室收缩压>35 mmHg)动脉瘤。手术策略包括30例患者(79%)行缩窄动脉成形术,8例患者(21%)行切除并植入移植物。平均住院时间为6.0±2.2天。无早期死亡病例。3例患者(8%)发生晚期死亡,与心脏无关。8%的患者发生晚期再次手术,与PA瘤无关。所有高压动脉瘤和直径大于8 cm的动脉瘤在标本病理检查中均显示有晚期中层坏死。

结论

PA瘤是一种真实存在的疾病,手术修复的发病率和死亡率较低。可根据解剖位置进行动脉瘤缝合或动脉瘤切除术。无论PA大小,由于晚期中层坏死的发生,我们建议对高压动脉瘤进行干预。

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