肾小管间质性肾炎和葡萄膜炎综合征（TINU）。免疫抑制治疗。
Tubulointerstitial nephritis and uveitis syndrome (TINU). Treatment with immunosuppressive therapy.
作者信息
Rueda-Rueda T, Sánchez-Vicente J L, Moruno-Rodríguez A, Castilla-Martino M, López-Herrero F, Contreras-Díaz M, Molina-Socola F, Sáez-Ortega L, Muñoz-Morales A
机构信息
Departamento de Oftalmología, Hospital Universitario Virgen del Rocío, Sevilla, España.
Departamento de Oftalmología, Hospital Universitario Virgen del Rocío, Sevilla, España.
出版信息
Arch Soc Esp Oftalmol (Engl Ed). 2018 Jan;93(1):47-51. doi: 10.1016/j.oftal.2017.01.008. Epub 2017 Jun 22.
CASE REPORT
Two cases of tubulointerstitial nephritis and uveitis are presented. Immunosuppressive therapy was required to control the uveitis. Contrary to that usually described, uveitis became chronic, which made immunosuppressive therapy necessary. Nephritis was successfully treated with steroids.
DISCUSSION
Tubulointerstitial nephritis and uveitis syndrome is an under-diagnosed disorder and requires clinical suspicion due to there being no specific laboratory study available. Recurrences and relapses of ocular inflammation are common. Immunosuppressive therapy is not often needed.
病例报告
本文介绍了两例肾小管间质性肾炎合并葡萄膜炎的病例。需要进行免疫抑制治疗来控制葡萄膜炎。与通常描述的情况相反，葡萄膜炎发展为慢性，这使得免疫抑制治疗成为必要。肾炎通过类固醇治疗成功治愈。
讨论
肾小管间质性肾炎-葡萄膜炎综合征是一种诊断不足的疾病，由于没有特定的实验室检查方法，因此需要临床怀疑。眼部炎症的复发很常见。通常不需要免疫抑制治疗。
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