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隐睾的流式细胞术分析

Flow cytometric analysis of the maldescended testis.

作者信息

Hacker-Kolm U, Kleinhans G, Göhde W

出版信息

Andrologia. 1985 Jul-Aug;17(4):389-94. doi: 10.1111/j.1439-0272.1985.tb01027.x.

DOI:10.1111/j.1439-0272.1985.tb01027.x
PMID:2864883
Abstract

Flow cytometric measurements of the cellular DNA contents of 16 testicular biopsies of 15 patients with maldescended testes were performed. 2 patients were children. 11 patients of pubescent or adult age had no haploid germ cells in the tissue of their maldescended testis. One patient with a testis mobilis had about a normal percentage of haploid germ cells. In one patient a malignant tumor was detected unexpectedly by an aneuploid stem line at 2.2 c. Flow cytometric analysis of human testicular biopsy material is an easy and a fast way to quantify the function of spermatogenesis and detect malignancies.

摘要

对15例隐睾患者的16份睾丸活检组织进行了细胞DNA含量的流式细胞术测量。其中2例为儿童。11例青春期或成年患者的隐睾组织中没有单倍体生殖细胞。1例睾丸可活动的患者单倍体生殖细胞比例大致正常。在1例患者中,通过非整倍体干细胞系在2.2c处意外检测到恶性肿瘤。对人类睾丸活检材料进行流式细胞术分析是一种简单快速的方法,可用于量化精子发生功能并检测恶性肿瘤。

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