高密度脂蛋白在天然免疫中的促炎与抗炎作用。
Pro- versus Anti-inflammatory Actions of HDLs in Innate Immunity.
机构信息
Faculty of Medicine, School of Medical Sciences, University of New South Wales, Sydney NSW 2031, Australia.
Department of Internal Medicine III, Division of Nephrology & Dialysis, Medical University of Vienna, 1090 Vienna, Austria.
出版信息
Cell Metab. 2017 Jul 5;26(1):2-3. doi: 10.1016/j.cmet.2017.04.007. Epub 2017 Jun 22.
High-density lipoproteins (HDLs) can inhibit inflammatory cytokine expression on innate immune cells, but sometimes they promote cytokine production as suggested in a recent article in Cell Metabolism by van der Vorst et al. (2017). Kopecky et al. point out that the origin, handling, and storage conditions of HDL preparations dictate their functional properties and can specifically affect immune cells to evoke a pro-inflammatory response.
高密度脂蛋白 (HDL) 可以抑制先天免疫细胞中炎症细胞因子的表达，但 van der Vorst 等人最近在《细胞代谢》（Cell Metabolism）上发表的一篇文章表明，有时它们也会促进细胞因子的产生。Kopecky 等人指出，HDL 制剂的来源、处理和储存条件决定了它们的功能特性，并且可以特异性地影响免疫细胞，引发炎症反应。
Zotero 插件