利用在线同位素分离技术生产用于核医学的高比活度放射性核素的初步研究。
A preliminary study for the production of high specific activity radionuclides for nuclear medicine obtained with the isotope separation on line technique.
作者信息
Borgna F, Ballan M, Corradetti S, Vettorato E, Monetti A, Rossignoli M, Manzolaro M, Scarpa D, Mazzi U, Realdon N, Andrighetto A
机构信息
Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Via Marzolo 5, 35131 Padova, Italy.
Laboratori Nazionali di Legnaro, Istituto Nazionale di Fisica Nucleare, Viale dell'Università 2, 35020 Legnaro, PD, Italy.
出版信息
Appl Radiat Isot. 2017 Sep;127:214-226. doi: 10.1016/j.apradiso.2017.06.022. Epub 2017 Jun 17.
Radiopharmaceuticals represent a fundamental tool for nuclear medicine procedures, both for diagnostic and therapeutic purposes. The present work aims to explore the Isotope Separation On-Line (ISOL) technique for the production of carrier-free radionuclides for nuclear medicine at SPES, a nuclear physics facility under construction at INFN-LNL. Stable ion beams of strontium, yttrium and iodine were produced using the SPES test bench (Front-End) to simulate the production of Sr, Y, I and I and collected with good efficiency on suitable targets.
放射性药物是核医学程序的基本工具，可用于诊断和治疗目的。本工作旨在探索在线同位素分离（ISOL）技术，以在SPES（意大利国家核物理研究所莱尼亚罗国家实验室正在建设的一个核物理设施）生产用于核医学的无载体放射性核素。使用SPES试验台（前端）产生了稳定的锶、钇和碘离子束，以模拟锶、钇、碘和碘的生产，并在合适的靶上高效收集。
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