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[儿茶酚胺给药期间心输出量变化的决定因素分析]

[Analysis of the factors determining the change in cardiac output during administration of catecholamines].

作者信息

Osadchiĭ L I, Balueva T V, Sergeev I V

出版信息

Biull Eksp Biol Med. 1985 Oct;100(10):387-90.

PMID:2864964
Abstract

Electromagnetic flow metering was used in acute experiments on cats to study the cardiac output (CO) and venous return (VR) changes under pressor reactions in response to noradrenaline (NA) and adrenaline (A) infusion. The CO increased in 2/3 and decreased in 1/3 of all observations in response to NA infusion. In half of observations, the VR had the same line of changes as the CO. Similar changes in the CO and VR were obtained after A infusion. The blockade of beta- and M-cholinoreceptors did not affect the magnitude of CO changes in response to NA infusion but played a certain role in response to A infusion. The level of the arterial blood pressure under which the increase of the CO in response to NA infusion was mostly recorded has been established.

摘要

在对猫进行的急性实验中,采用电磁流量测量法来研究在输注去甲肾上腺素(NA)和肾上腺素(A)引发的升压反应下,心输出量(CO)和静脉回流(VR)的变化。在所有观察中,2/3 的情况下输注 NA 后 CO 增加,1/3 的情况下 CO 减少。在一半的观察中,VR 的变化趋势与 CO 相同。输注 A 后,CO 和 VR 出现了类似的变化。β-和 M-胆碱能受体的阻断并不影响输注 NA 后 CO 变化的幅度,但在输注 A 时发挥了一定作用。已确定了在输注 NA 后 CO 增加最常出现时的动脉血压水平。

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