可见光光催化条件下N-亚磺酰亚胺的不对称自由基烷基化反应
Asymmetric radical alkylation of N-sulfinimines under visible light photocatalytic conditions.
作者信息
Garrido-Castro Alberto F, Choubane Houcine, Daaou Mortada, Maestro M Carmen, Alemán José
机构信息
Departamento de Química Orgánica (Módulo 1), Facultad de Ciencias, Universidad Autónoma de Madrid, 28049, Madrid, Spain.
出版信息
Chem Commun (Camb). 2017 Jul 6;53(55):7764-7767. doi: 10.1039/c7cc03724d.
PMID:28650038
Abstract
In this communication, a new photocatalytic strategy for the addition of alkyl-radical derivatives to N-sulfinimines with complete diastereoselectivity and moderate to good yields is presented. This is the first asymmetric photocatalytic addition to N-sulfinimines under visible light irradiation with smooth conditions and functional group tolerance.
摘要
在本通讯中，提出了一种新的光催化策略，可使烷基自由基衍生物与N-亚磺酰亚胺进行加成反应，具有完全的非对映选择性，产率适中至良好。这是在可见光照射下，在温和条件和官能团耐受性下首次对N-亚磺酰亚胺进行不对称光催化加成反应。
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