Univ Lyon, INSA-Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS, UMR 5220, U1206, F-69616, Villeurbanne, France.
Radiologie et Imagerie médicale diagnostique et thérapeutique, Hôpital François Mitterrand, Dijon, France.
J Magn Reson Imaging. 2018 Apr;47(4):1022-1033. doi: 10.1002/jmri.25799. Epub 2017 Jun 26.
To assess the T ρ and T values in the hip cartilage of healthy volunteers and to evaluate the reproducibility of these measurements.
The right hip joint of 30 asymptomatic volunteers was explored with 3T magnetic resonance imaging (MRI). Quantitative 3D T ρ- and T -maps sequences were repeated twice with a 30-minute delay (immediate reproducibility). The same protocol was repeated 14 days later (short-term reproducibility). Immediate and short-term reproducibility were estimated using coefficients of variation and correlation concordance coefficients (CCC). The precisions of the measurements were estimated by the ratio of the standard deviations. A mixed linear model was used to analyze the effect of patient's characteristics on T ρ and T values.
Immediate reproducibility was significantly better than short-term reproducibility for T ρ (CCC of 0.75 versus 0.55; P = 0.007) and T (CCC 0.65 versus 0.32; P < 0.001). The precisions of the measurements were estimated between 5.5% and 9.1%. Median T ρ values were 6.0 msec higher in women than in men (P = 0.006), with no significant influence of age, body mass index (BMI), or sports activity. Median T values were not significantly different between men and women (0.4 msec lower in women; P = 0.76). There was no significant influence of age, BMI, or sports activity. T ρ and T values were lower in lateral regions than in medial regions (4.9 msec and 2.5 msec lower respectively; P < 0.0001).
Immediate reproducibility of T ρ and T values is better than short-term, with limited effect of 30 minutes decubitus. T ρ values are significantly higher in women.
2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018;47:1022-1033.
评估健康志愿者髋关节软骨中的 Tρ 和 T 值，并评估这些测量值的可重复性。
对 30 名无症状志愿者的右侧髋关节进行 3T 磁共振成像（MRI）检查。使用定量 3D Tρ 和 T-图序列重复两次，两次之间间隔 30 分钟（即时可重复性）。14 天后重复相同的方案（短期可重复性）。使用变异系数和一致性相关系数（CCC）评估即时和短期可重复性。通过标准差比来估计测量的精密度。使用混合线性模型分析患者特征对 Tρ 和 T 值的影响。
Tρ 的即时可重复性明显优于短期可重复性（CCC 分别为 0.75 和 0.55；P=0.007），T 的即时可重复性也明显优于短期可重复性（CCC 分别为 0.65 和 0.32；P<0.001）。测量的精密度估计在 5.5%到 9.1%之间。女性的 Tρ 值中位数比男性高 6.0 毫秒（P=0.006），而年龄、体重指数（BMI）或运动活动对其没有显著影响。男性和女性的 T 值中位数无显著差异（女性低 0.4 毫秒；P=0.76）。年龄、BMI 或运动活动对其均无显著影响。外侧区域的 Tρ 和 T 值均低于内侧区域（分别低 4.9 毫秒和 2.5 毫秒；P<0.0001）。
Tρ 和 T 值的即时可重复性优于短期可重复性，30 分钟卧床休息的影响有限。女性的 Tρ 值明显更高。
2 技术效果：第 2 阶段。J. Magn. Reson. Imaging 2018；47：1022-1033。
