Lana Silvia, Ganazzoli Chiara, Crisi Girolamo
Azienda Ospedaliero Universitaria di Parma, Italy.
Neuroradiol J. 2018 Apr;31(2):182-185. doi: 10.1177/1971400917714804. Epub 2017 Jun 26.
Hypertrophic olivary degeneration (HOD) is a rare trans-synaptic neuronal degeneration of the inferior olivary nucleus caused by an injury to the dentato-rubro-olivary connection, also known as Guillain-Mollaret triangle. It leads to hypertrophy of the affected nucleus rather than atrophy and is characterized by hyperintensity on T2-weighted images. Unilateral and bilateral cases are described. We present a case of a 70-year-old patient affected by a tumor inside the fourth ventricle who suffered from diplopia and right seventh cranial nerve palsy. He underwent surgery and developed left seventh cranial nerve palsy. Three months after resection, magnetic resonance imaging revealed the appearance of bilateral HOD. This is the first report of bilateral HOD occurrence after surgical bilateral damage of the rubro-olivary fibers running in central tegmental tracts.
肥大性橄榄体变性（HOD）是一种罕见的跨突触神经元变性，由齿状红核橄榄体连接损伤引起，该连接也称为 Guillain-Mollaret 三角。它导致受影响的核肥大而非萎缩，其特征是在 T2 加权图像上呈高信号。有单侧和双侧病例的描述。我们报告一例 70 岁患者，其第四脑室内有肿瘤，患有复视和右侧第七颅神经麻痹。他接受了手术，术后出现左侧第七颅神经麻痹。切除术后三个月，磁共振成像显示双侧 HOD 的表现。这是在中央被盖束中走行的红核橄榄体纤维受到双侧手术损伤后发生双侧 HOD 的首例报告。
