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机器人辅助根治性膀胱切除术与开放性根治性膀胱切除术治疗膀胱癌的比较:文献回顾和随机试验。

Robotic-assisted radical cystectomy versus open radical cystectomy for management of bladder cancer: review of literature and randomized trials.

机构信息

Department of Urology, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Pl, New York, NY 10029, USA.

出版信息

Future Oncol. 2017 Jun;13(13):1195-1204. doi: 10.2217/fon-2017-0004. Epub 2017 Jun 26.

Abstract

Among the many milestones in the last several decades in the management of muscle-invasive bladder cancer and high-risk nonmuscle-invasive bladder cancer including the extension of the standard lymph node dissection and the use of neoadjuvant chemotherapy, minimally invasive techniques have gained traction as an attractive option for radical cystectomy. Open radical cystectomy is plagued with high rates of perioperative and postoperative morbidity and mortality, and as robotic assistance has demonstrated benefits in other arenas of surgery and urology, the evolution of the approach to radical cystectomy has likewise incorporated robotic assistance. We thus sought to critically review the literature comparing open radical cystectomy with robotic-assisted radical cystectomy. Perioperative and oncologic outcomes as well as cost analyses and health-related quality of life were compared between the two approaches, and identified manuscripts were categorized according to level of evidence.

摘要

在过去几十年中,在肌肉浸润性膀胱癌和高危非肌肉浸润性膀胱癌的治疗方面取得了许多里程碑式的进展,包括扩大标准淋巴结清扫术和新辅助化疗的应用,微创技术作为根治性膀胱切除术的一种有吸引力的选择已经得到了广泛的关注。开放性根治性膀胱切除术存在较高的围手术期和术后发病率和死亡率,并且随着机器人辅助技术在其他外科和泌尿科领域显示出优势,根治性膀胱切除术的方法也同样采用了机器人辅助技术。因此,我们试图对比较开放性根治性膀胱切除术和机器人辅助根治性膀胱切除术的文献进行批判性回顾。比较了两种方法的围手术期和肿瘤学结果以及成本分析和健康相关生活质量,并根据证据水平对已确定的文献进行了分类。

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