Dashow L, Epple A
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1985;82(1):119-22. doi: 10.1016/0742-8413(85)90217-8.
The widely scattered cardiovascular chromaffin cells of Petromyzon marinus appear to form an intrinsic control system of circulatory function. In response to blood-borne stimuli, a checkpoint-like accumulation of epinephrine cells in the heart releases its hormone; epinephrine, in turn, stimulates the release of norepinephrine, and probably also of dopamine, from other cardiovascular chromaffin cells. The myocardium seems to be a major target of norepinephrine. On the other hand, high disappearance rates of epinephrine and dopamine in the gills point to these organs as possible major targets of the latter two secretions. Carbon dioxide and hypovolemia are strong stimuli of catecholamine release.
海七鳃鳗广泛分布的心血管嗜铬细胞似乎构成了循环功能的内在控制系统。响应血源性刺激，心脏中肾上腺素细胞呈检查点样聚集并释放其激素；肾上腺素继而刺激其他心血管嗜铬细胞释放去甲肾上腺素，可能还刺激多巴胺释放。心肌似乎是去甲肾上腺素的主要靶标。另一方面，鳃中肾上腺素和多巴胺的高消失率表明这些器官可能是后两种分泌物的主要靶标。二氧化碳和血容量减少是儿茶酚胺释放的强烈刺激因素。
