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[秋水仙碱对乙酰胆碱和毛果芸香碱作用于七鳃鳗（Lampetra planeri，布洛赫）离体心室的影响]

[Influence of colchicine on the effects of acetylcholine and pilocarpine on isolated ventricle of the ammocete Lampetra planeri (Bloch)].

作者信息

Lignon M J, Wolff E

出版信息

C R Acad Hebd Seances Acad Sci D. 1975 Jan 13;280(2):181-4.

PMID:808279
Abstract

Colchicine inhibits the positive chronotopic effects of acetylcholine and of pilocarpine of the isolated ammocoete heart ventricle. This positive chronotropic effect is due to a release of catecholamines from the chromaffin cells of the lamprey heart. The action of colchicine, which does not result from its curare-like effect, suggests that acetylcholine induces release of catecholamines by exycytosis.

摘要

秋水仙碱可抑制分离的七鳃鳗幼体心脏心室中乙酰胆碱和毛果芸香碱的正性变时作用。这种正性变时作用是由于七鳃鳗心脏嗜铬细胞释放儿茶酚胺所致。秋水仙碱的作用并非源于其箭毒样效应，这表明乙酰胆碱通过胞吐作用诱导儿茶酚胺释放。

相似文献

1
[Influence of colchicine on the effects of acetylcholine and pilocarpine on isolated ventricle of the ammocete Lampetra planeri (Bloch)].[秋水仙碱对乙酰胆碱和毛果芸香碱作用于七鳃鳗（Lampetra planeri，布洛赫）离体心室的影响]
C R Acad Hebd Seances Acad Sci D. 1975 Jan 13;280(2):181-4.
2
[Action of adrenergic and cholinergic substances on the spontaneous activity of isolated ventricle of the ammocete of Lampetra planeri].[肾上腺素能和胆碱能物质对七鳃鳗幼体离体心室自发活动的作用]
C R Acad Hebd Seances Acad Sci D. 1971 Oct 11;273(15):1302-5.
3
[Action of K+, Na+, Ca2+ and Ba2+ ions on the spontaneous rhythm of the isolated ventricle of ammocoete Lampetra planeri].[钾离子、钠离子、钙离子和钡离子对七鳃鳗幼体（Lampetra planeri）离体心室自发节律的作用]
C R Seances Soc Biol Fil. 1971;165(2):407-12.
4
Colchicine inhibits adrenal medullary secretion evoked by acetylcholine without affecting that evoked by potassium.秋水仙碱可抑制由乙酰胆碱引起的肾上腺髓质分泌，但不影响由钾引起的肾上腺髓质分泌。
Br J Pharmacol. 1972 May;45(1):129-32.
5
Electrophoretic pattern of the haemolyzate in specimens of Lampetra planeri (Bloch), captured in Abruzzo, in relation to the developmental cycle.
Riv Biol. 1976 Jul-Dec;69(3-4):343-58.
6
Effect of acetylcholine on isolated cat and rabbit heart ventricle preparation.乙酰胆碱对离体猫和兔心室标本的作用。
Acta Pharmacol Toxicol (Copenh). 1973;32(5):345-52.
7
Plasma catecholamines in the lamprey: intrinsic cardiovascular messengers?七鳃鳗血浆中的儿茶酚胺：内在的心血管信使？
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1985;82(1):119-22. doi: 10.1016/0742-8413(85)90217-8.
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Ultrastructure of the presumed ion-transporting cells in the gills of ammocoete lampreys, Lampetra fluviatilis (L.) and Lampetra planeri (Bloch).河七鳃鳗（Lampetra fluviatilis (L.)）和溪流七鳃鳗（Lampetra planeri (Bloch)）鳃中假定的离子转运细胞的超微结构。
Cell Tissue Res. 1975 Nov 12;163(3):327-41. doi: 10.1007/BF00219467.
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[Blocking action of snake venom polypeptides on the cholinoreceptive membranes of the lampern, Lampetra fluviatilis].[蛇毒多肽对七鳃鳗（Lampetra fluviatilis）胆碱能感受膜的阻断作用]
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10
A possible role of microtubules in catecholamine release from the adrenal medulla: effect of colchicine, vinca alkaloids and deuterium oxide.微管在肾上腺髓质儿茶酚胺释放中的可能作用：秋水仙碱、长春花生物碱和重水的影响
J Pharmacol Exp Ther. 1971 Apr;177(1):102-8.