Marin Luis, Rowan Raymond, Mantilla Ana, Olupona Bamidele, MacIntyre Ann
J Am Podiatr Med Assoc. 2017 May;107(3):231-239. doi: 10.7547/15-180.
Serratia marcescens is a ubiquitous, facultatively anaerobic, gram-negative bacillus that has been cited to cause infection in immunocompromised populations. In the literature, S marcescens infections of the lower extremity have presented as granulomatous ulceration, abscess, bullous cellulitis, and necrotizing fasciitis. Herein we present a series of three cases of lower-extremity infections in which S marcescens was the sole or a contributing pathogen. We discuss the commonalities of these three cases as well as with those previously cited. All three patients presented with some combination of a similar set of clinical characteristics, including bullae formation, liquefactive necrosis, and black necrotic eschar. All three patients were diabetic and had peripheral vascular disease.
粘质沙雷氏菌是一种普遍存在的兼性厌氧革兰氏阴性杆菌，据报道可在免疫功能低下人群中引起感染。在文献中，下肢粘质沙雷氏菌感染表现为肉芽肿性溃疡、脓肿、大疱性蜂窝织炎和坏死性筋膜炎。在此，我们报告了三例下肢感染病例，其中粘质沙雷氏菌是唯一或主要病原体。我们讨论了这三例病例与先前报道病例的共同点。所有三名患者均表现出一组相似临床特征的某种组合，包括水疱形成、液化性坏死和黑色坏死焦痂。所有三名患者均患有糖尿病且有外周血管疾病。
