一名患有X连锁慢性肉芽肿病的4岁男孩因贝塞斯达颗粒杆菌感染导致暴发性脓毒症
Fulminant Sepsis Due to Granulibacter bethesdensis in a 4-Year-Old Boy With X-Linked Chronic Granulomatous Disease.
作者信息
Mayer Erick F, Gialanella Philip, Munjal Iona, Cunningham-Rundles Charlotte, Dara Jasmeen
机构信息
From the *Department of Pediatrics, Children's Hospital at Montefiore and Albert Einstein College of Medicine, Bronx, †Department of Microbiology and Pathology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, and ‡Department of Medicine, Mount Sinai Hospital and Icahn School of Medicine, New York, New York.
出版信息
Pediatr Infect Dis J. 2017 Dec;36(12):1165-1166. doi: 10.1097/INF.0000000000001659.
Abstract
Granulibacter bethesdensis is a Gram-negative bacillus described as a pathogen exclusively in patients with chronic granulomatous disease, a phagocytic disorder that impairs the ability to clear catalase-producing organisms. Granulibacter usually causes chronic and recurrent lymphadenopathies. We report the fatal case of a 4-year-old boy with chronic granulomatous disease, who presented with sepsis after a few days of abdominal pain and diarrhea.
摘要
贝塞斯达颗粒杆菌是一种革兰氏阴性杆菌，据描述它仅在患有慢性肉芽肿病的患者中作为病原体出现，慢性肉芽肿病是一种吞噬功能障碍性疾病，会损害清除产过氧化氢酶生物体的能力。颗粒杆菌通常会导致慢性复发性淋巴结病。我们报告了一例4岁慢性肉芽肿病男孩的致命病例，该男孩在出现腹痛和腹泻几天后发生了败血症。
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