腹腔镜妇科手术中使用的体内共聚焦激光内镜检查：一种有前景的工具。
In vivo confocal laser endomicroscopy during laparoscopy for gynecological surgery: A promising tool.
作者信息
Chene G, Chauvy L, Buenerd A, Moret S, Nadaud B, Beaufils E, Le Bail-Carval K, Chabert P, Mellier G, Lamblin G
机构信息
Department of gynecology, hôpital femme mère enfant (HFME), CHU de Lyon Est, 69000 Lyon, France; University Claude-Bernard Lyon 1, EMR 3738, 69000 Lyon, France.
Department of gynecology, hôpital femme mère enfant (HFME), CHU de Lyon Est, 69000 Lyon, France.
出版信息
J Gynecol Obstet Hum Reprod. 2017 Sep;46(7):565-569. doi: 10.1016/j.jogoh.2017.06.003. Epub 2017 Jun 23.
INTRODUCTION
To investigate the technical feasibility of optical biopsy (probe-based confocal laser endomicroscopy [pCLE]) during laparoscopy and by the vaginal route in the exploration of pelvic gynecological cancers.
METHODS
Prospective study including 31 patients undergoing laparoscopic hysterectomy (benign or malignant indication). Confocal microlaparoscopy (analysis of tubes, ovaries, and depending on the type de cancer, pelvic adenopathies) and optical biopsy of the endometrium were first carried out by the vaginal route under general anesthesia. The surgical procedure was then carried out.
RESULTS
Thirty-one consecutive patients were included (16 for benign hysterectomy, 12 for endometrial cancer and 3 for ovarian carcinoma). pCLE offered dynamic pictures that were correlated with the histopathological images.
DISCUSSION AND CONCLUSION
pCLE provides high resolution imaging of cancerous and benign tissues in real-time similar to histopathological results. Both feasibility and safety were confirmed.
引言
探讨在腹腔镜检查过程中以及经阴道途径对盆腔妇科癌症进行光学活检（基于探头的共聚焦激光显微内镜检查[pCLE]）的技术可行性。
方法
前瞻性研究纳入31例行腹腔镜子宫切除术的患者（良性或恶性指征）。首先在全身麻醉下经阴道途径进行共聚焦显微腹腔镜检查（分析输卵管、卵巢，并根据癌症类型分析盆腔淋巴结）和子宫内膜光学活检。然后进行手术操作。
结果
连续纳入31例患者（16例行良性子宫切除术，12例为子宫内膜癌，3例为卵巢癌）。pCLE提供了与组织病理学图像相关的动态图像。
讨论与结论
pCLE可实时提供与组织病理学结果相似的癌组织和良性组织的高分辨率成像。证实了其可行性和安全性。
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