Badawy S Z, Marshall L, Cuenca V
Int J Fertil. 1985;30(2):48-52.
Thirty-nine patients with pelvic endometriosis and 45 patients with no evidence of endometriosis were entered in this study. The mean age was 29 years for each group. The volume of peritoneal fluid showed an increase towards the end of the cycle in both groups. Although the volume was higher in the endometriosis group than the control group, the difference between them was not significant. The concentration of prostaglandins F2 alpha and E2 was higher in patients with endometriosis than in the control group. The difference was significant (P less than 0.05) during days 9-16 and 17-24 for both prostaglandins, and during days 1-8 for prostaglandin F 2 alpha only. The high concentration of prostaglandins in the periovulatory and early luteal phases of the cycle may have adverse effects on tubo-ovarian function in endometriosis patients. Prostaglandin studies in peritoneal fluid are of significance during days 9-24 of the cycle when the effect of regurgitated menstrual fluid in the early phase of days 1-8 may be avoided.
本研究纳入了39例盆腔子宫内膜异位症患者和45例无子宫内膜异位症证据的患者。每组的平均年龄均为29岁。两组患者的腹腔液体积在月经周期末期均呈现增加趋势。虽然子宫内膜异位症组的腹腔液体积高于对照组，但两组之间的差异并不显著。子宫内膜异位症患者体内前列腺素F2α和E2的浓度高于对照组。两种前列腺素在第9 - 16天和第17 - 24天，以及前列腺素F2α仅在第1 - 8天的差异均具有统计学意义（P < 0.05）。月经周期中排卵期和黄体早期前列腺素的高浓度可能会对子宫内膜异位症患者的输卵管 - 卵巢功能产生不利影响。在月经周期的第9 - 24天进行腹腔液中前列腺素的研究具有重要意义，因为这样可以避免在第1 - 8天早期反流的月经液的影响。
