Sanderson P J, Haji T C
J Hosp Infect. 1985 Sep;6(3):257-64.
Seven babies born to 28 mothers who were vaginal carriers of group B streptococci and who bathed or showered with chlorhexidine during the last 2 weeks of pregnancy were colonized with an organism of the same phage type as their mothers. In contrast, nine babies of 14 carrier mothers who were given no instructions regarding washing were colonized with the same phage type as their mothers. Ten of the 84 sites sampled for group B streptococci on the babies born to mothers using chlorhexidine were positive, whereas 17 of 42 were positive in the babies born to control mothers. This trial suggests that whole body washing with chlorhexidine may reduce the transfer of group B streptococci from mothers to infants, but did not exclude the possibility that body washing by itself may have a similar effect.
28位母亲是B族链球菌阴道携带者,她们在妊娠最后两周用洗必泰洗澡或淋浴,所生的7名婴儿被与母亲相同噬菌体类型的微生物定植。相比之下,14位携带菌母亲中9名未得到关于清洗的指导,她们所生婴儿被与母亲相同噬菌体类型的微生物定植。在使用洗必泰的母亲所生婴儿中,为检测B族链球菌而采样的84个部位中有10个呈阳性,而在对照母亲所生婴儿中,42个部位中有17个呈阳性。该试验表明,用洗必泰全身清洗可能会减少B族链球菌从母亲向婴儿的传播,但并未排除身体清洗本身可能有类似效果的可能性。