Zuk Grzegorz, Ciecwierz Dariusz, Cwalina Natalia, Gruchala Marcin, Cuculi Florim
First Department of Cardiology, Medical University of Gdansk, Debinki 7, 80-952, Gdansk, Poland.
Cardiol J. 2017;24(4):426-435. doi: 10.5603/CJ.a2017.0072. Epub 2017 Jun 27.
Fractional flow reserve (FFR) is an evidence-based diagnostic tool of physiological significance of coronary artery stenosis in patients with stable coronary artery disease (CAD). Due to microvascular dysfunction in acute coronary syndrome (ACS), information obtained from FFR assessment could be less reliable and, thus, its clinical role remains controversial. Indeed, results of currently published studies are essentially discrepant. Only a few randomized clinical trials have been performed showing the efficacy of FFR-guided percutaneous coronary intervention in ACS. Consequently, its role in acute scenarios remains substantially understudied. Herein, is presented the current state of knowledge re-garding FFR use in ACS setting. (Cardiol J 2017; 24, 4: 426-435).
血流储备分数（FFR）是一种基于证据的诊断工具，用于评估稳定性冠心病（CAD）患者冠状动脉狭窄的生理意义。由于急性冠状动脉综合征（ACS）存在微血管功能障碍，通过FFR评估获得的信息可能不太可靠，因此其临床作用仍存在争议。事实上，目前已发表的研究结果基本不一致。仅有少数随机临床试验表明FFR指导的经皮冠状动脉介入治疗在ACS中有效。因此，其在急性情况下的作用仍未得到充分研究。本文介绍了在ACS背景下使用FFR的当前知识状况。（《心脏病学杂志》2017年；24卷，第4期：426 - 435页）
