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机器人辅助微创经椎间孔腰椎椎间融合术与传统开放手术治疗腰椎滑脱症的疗效

[Effects of robot-assisted minimally invasive transforaminal lumbar interbody fusion and traditional open surgery in the treatment of lumbar spondylolisthesis].

作者信息

Cui G Y, Tian W, He D, Xing Y G, Liu B, Yuan Q, Wang Y Q, Sun Y Q

机构信息

Department of Spinal Surgery, Beijing Jishuitan Hospital, Fourth Medical College of Peking University, Beijing 100035, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2017 Jul 1;55(7):543-548. doi: 10.3760/cma.j.issn.0529-5815.2017.07.013.

Abstract

To compare the clinical effects of robot-assisted minimally invasive transforaminal lumbar interbody fusion (TLIF) and traditional open TLIF in the treatment of lumbar spondylolisthesis. A total of 41 patients with lumbar spondylolisthesis accepted surgical treatment in Department of Spinal Surgery of Beijing Jishuitan Hospital From July 2015 to April 2016 were retrospectively analyzed. There were 16 cases accepted robot-assisted minimally invasive TLIF and 25 accepted traditional open TLIF. The operation time, X-ray radiation exposure time, perioperative bleeding, drainage volume, time of hospitalization, time for pain relief, time for ambulatory recovery, visual analogue scale (VAS), Oswestry disability index (ODI) and complications were compared. test and χ(2) were used to analyze data. There were no significant difference in gender, age, numbers, degrees, pre-operative VAS and ODI in spondylolisthesis (all >0.05). Compared with traditional open TLIF group, the robot-assisted minimally invasive TLIF group had less perioperative bleeding ((187.5±18.4) ml . (332.1±23.5) ml), less drainage volume ((103.1±15.6) ml . (261.3±19.8) ml), shorter hospitalization ((7.8±1.9) days . (10.0±1.6) days), shorter time for pain relief ((2.8±1.0) days . (5.2±1.1) days), shorter time for ambulatory recovery ((1.7±0.9) days . (2.9±1.3) days) and less VAS of the third day postoperatively (2.2±0.9 . 4.2±2.4) (=2.762-16.738, all <0.05), but need more operation time ((151.3±12.3) minutes . (102.2±7.1) minutes) and more X-ray radiation exposure ((26.1±3.3) seconds . (5.5±2.1) seconds) (=6.125, 15.168, both <0.01). In both groups ODI was significantly lower in final follow-up than that of the pre-operation (=12.215, 14.036, <0.01). Intervertebral disc height of the final follow-up in both groups were significantly larger than that of the preoperation (robot-assisted minimally invasive TLIF group: (11.8 ± 2.8) mm . (7.5 ± 1.9) mm, traditional open TLIF group: (12.7 ± 2.5) mm . (7.9±2.0) mm), and so was the lumbar lordosis angle (robot-assisted minimally invasive TLIF group: (48.7±9.2)°. (39.6±7.9)°, traditional open TLIF group: (50.1±10.8)°. (41.4±8.8)°), the lordosis angle of the slippage segment (robot-assisted minimally invasive TLIF group: (18.7±5.6)°. (10.9±3.8)°, traditional open TLIF group: (17.6±6.1)°.(8.7±3.2)°) (=4.128-16.738, all <0.01). Slippage rate of the final follow-up in both groups were significantly smaller than those of the pre-operation (robot-assisted minimally invasive TLIF group: (5.3±2.3) % . (27.8±7.2) %, traditional open TLIF group: (6.6±2.8) % . (29.1±9.5) %) (=11.410, 18.504, both <0.01). There was no difference of the upper data between two groups (=0.106-1.227, >0.05). The results of the post-operative CT showed that the pedicle screws in the robot-assisted minimally invasive TLIF group were more precisely placed than traditional open TLIF group (χ(2)=4.247, =0.039). The mean follow-up time was 8 months (ranging from 3 to 12 months). There were no significant difference in outcomes between the two groups (χ(2)=0.366, =0.545). In the treatment of lumbar spondylolisthesis, Robot-assisted minimally invasive TLIF can lead to less perioperative bleeding, less post-operative pain, and quicker recovery than traditional open TLIF surgery, but it needs more operation time and radiation exposure.

摘要

比较机器人辅助微创经椎间孔腰椎椎间融合术(TLIF)与传统开放TLIF治疗腰椎滑脱症的临床效果。回顾性分析2015年7月至2016年4月在北京积水潭医院脊柱外科接受手术治疗的41例腰椎滑脱症患者。其中16例行机器人辅助微创TLIF,25例行传统开放TLIF。比较两组手术时间、X线辐射暴露时间、围手术期出血量、引流量、住院时间、疼痛缓解时间、行走恢复时间、视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)及并发症情况。采用t检验和χ²检验分析数据。两组患者在性别、年龄、例数、滑脱程度、术前VAS及ODI等方面差异均无统计学意义(均P>0.05)。与传统开放TLIF组相比,机器人辅助微创TLIF组围手术期出血量少[(187.5±18.4)ml比(332.1±23.5)ml]、引流量少[(103.1±15.6)ml比(261.3±19.8)ml]、住院时间短[(7.8±1.9)天比(10.0±1.6)天]、疼痛缓解时间短[(2.8±1.0)天比(5.2±1.1)天]、行走恢复时间短[(1.7±0.9)天比(2.9±1.3)天],术后第3天VAS评分低(2.2±0.9比4.2±2.4)(t=2.762~16.738,均P<0.05),但手术时间长[(151.3±12.3)分钟比(102.2±7.1)分钟]、X线辐射暴露时间长[(26.1±3.3)秒比(5.5±2.1)秒](t=6.125、15.168,均P<0.01)。两组患者末次随访时ODI均较术前显著降低(t=12.215、14.036,P<0.01)。两组患者末次随访时椎间隙高度均较术前显著增大(机器人辅助微创TLIF组:(11.8±2.8)mm比(7.5±1.9)mm,传统开放TLIF组:(12.7±2.5)mm比(7.9±2.0)mm),腰椎前凸角亦如此(机器人辅助微创TLIF组:(48.7±9.2)°比(39.6±7.9)°,传统开放TLIF组:(50.1±10.8)°比(41.4±8.8)°),滑脱节段前凸角(机器人辅助微创TLIF组:(18.7±5.6)°比(10.9±3.8)°,传统开放TLIF组:(17.6±6.1)°比(8.7±3.2)°)(t=4.128~16.738,均P<0.01)。两组患者末次随访时滑脱率均较术前显著减小(机器人辅助微创TLIF组:(5.3±2.3)%比(27.8±7.2)%,传统开放TLIF组:(6.6±2.8)%比(29.1±9.5)%)(t=11.410、18.504,均P<0.01)。上述数据两组间差异无统计学意义(t=0.106~1.227,P>0.05)。术后CT结果显示,机器人辅助微创TLIF组椎弓根螺钉置入精度高于传统开放TLIF组(χ²=4.247,P=0.039)。平均随访时间8个月(3~12个月)。两组疗效差异无统计学意义(χ²=0.366,P=0.545)。在腰椎滑脱症治疗中,机器人辅助微创TLIF较传统开放TLIF手术围手术期出血少、术后疼痛轻、恢复快,但手术时间长,辐射暴露多。

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