1 Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
2 Division of Dermatology, The Ottawa Hospital, Ottawa, ON, Canada.
J Cutan Med Surg. 2017 Nov/Dec;21(6):553-555. doi: 10.1177/1203475417719043. Epub 2017 Jun 28.
Fingolimod is an immune-modulating drug used in the treatment of multiple sclerosis. Histoplasma capsulatum is a dimorphic fungus that can infect humans. Infection with the pathogen typically affects the lungs, but it is usually asymptomatic and self-limited. However, immunocompromised patients infected with the pathogen can present atypically, including the development of primary cutaneous lesions. We describe an interesting clinical case of a cutaneous H capsulatum infection in a patient treated with fingolimod.
芬戈莫德是一种用于治疗多发性硬化症的免疫调节药物。荚膜组织胞浆菌是一种双相真菌，可感染人类。感染该病原体通常影响肺部，但通常无症状且自限性。然而，感染该病原体的免疫功能低下患者可能表现为非典型症状，包括原发性皮肤损伤的发展。我们描述了一例有趣的临床病例，即接受芬戈莫德治疗的患者发生荚膜组织胞浆菌皮肤感染。
