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一名患有成人斯蒂尔病的免疫抑制患者的皮肤溃疡:原发性皮肤组织胞浆菌病?

Cutaneous ulcer in an immunosuppressed patient with adult onset Still's disease: primary cutaneous histoplasmosis?

作者信息

Lise Michelle Larissa Zini, Godinho Ronaldo Nunes, Brollo Flávia Moojen, Staub Henrique Luiz

机构信息

Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.

出版信息

An Bras Dermatol. 2014 May-Jun;89(3):532-4. doi: 10.1590/abd1806-4841.20142727.

Abstract

Histoplasmosis is caused by the dimorphic fungus Histoplasma capsulatum.Primary infection occurs through inhalation of spores from the air. Immunocompetent individuals are usually asymptomatic, but may develop pulmonary disease. Immunocompromised patients tend to present systemic histoplasmosis with cutaneous lesions occurring by secondary invasion. In this case report, we describe a probable primary cutaneous histoplasmosis (PCH) in a patient with adult onset Still's disease under immunosuppression.

摘要

组织胞浆菌病由双相真菌荚膜组织胞浆菌引起。原发性感染通过吸入空气中的孢子发生。免疫功能正常的个体通常无症状,但可能会发展为肺部疾病。免疫功能低下的患者往往会出现系统性组织胞浆菌病,并通过继发性侵袭出现皮肤病变。在本病例报告中,我们描述了一名成年斯蒂尔病患者在免疫抑制状态下可能发生的原发性皮肤组织胞浆菌病(PCH)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29f/4056725/78e316a4c05f/abd-89-03-0532-g01.jpg

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