Onyenekwu C P, Dada A O, Babatunde O T
Department of Chemical Pathology, Benjamin S. Carson (Snr) School of Medicine, Babcock University and Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria.
Department of Paediatrics, Benjamin S. Carson (Snr) School of Medicine, Babcock University and Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria.
Niger J Clin Pract. 2017 Jun;20(6):670-676. doi: 10.4103/1119-3077.196085.
The incidence of metabolic syndrome (MetS), is rapidly increasing in developing countries. However, the epidemiology of MetS is not well reported in the pediatric and young adult population. We determined the prevalence of MetS and its components among overweight and obese Nigerian adolescents and young adults presenting for university admission.
A cross-sectional study of overweight and obese adolescents and young adults was performed. Blood pressure readings were taken while participants were seated. Anthropometric measures of waist circumference, weight and height were also taken using standard protocols and the body mass index was computed thereafter. Venous blood for fasting plasma glucose, triglycerides and high density lipoprotein cholesterol was collected and assayed using standard laboratory methods. Metabolic syndrome was defined by the International Diabetes Federation criteria. Statistical significance was set at 0.05.
91 individuals (18 males) aged 18.1 ± 4.85 years were studied. 13 (14.3%) of them had MetS and 11 (84.6%) of these were adolescents. Abdominal obesity was prevalent in 89 (97.8%) participants, hypertension was prevalent in 39 (42.9%) participants and hyperglycaemia was prevalent in 5 (5.5%) participants. Hypertriglyceridaemia was least prevalent in one (1.1%) participant who did not have MetS. All the participants who had hyperglycaemia (5.5%) had MetS.
There is a high prevalence of MetS in obese and overweight Nigerian adolescents and young adults with the clustering of two components in half of the population. These findings have profound implications hence there is an urgent need to institute primary and secondary interventions in this population.
在发展中国家，代谢综合征（MetS）的发病率正在迅速上升。然而，儿科和青年人群中MetS的流行病学情况报道较少。我们确定了前来大学入学体检的超重和肥胖尼日利亚青少年及青年中MetS及其组成成分的患病率。
对超重和肥胖青少年及青年进行了一项横断面研究。参与者就座时测量血压。使用标准方案测量腰围、体重和身高的人体测量指标，随后计算体重指数。采集静脉血检测空腹血糖、甘油三酯和高密度脂蛋白胆固醇，并采用标准实验室方法进行测定。代谢综合征根据国际糖尿病联盟标准定义。统计学显著性设定为0.05。
研究了91名年龄在18.1±4.85岁的个体（18名男性）。其中13人（14.3%）患有MetS，其中11人（84.6%）为青少年。89名（97.8%）参与者存在腹型肥胖，39名（42.9%）参与者患有高血压，5名（5.5%）参与者存在高血糖。高甘油三酯血症在1名未患MetS的参与者中最为少见（1.1%）。所有存在高血糖的参与者（5.5%）均患有MetS。
肥胖和超重的尼日利亚青少年及青年中MetS的患病率很高，半数人群中存在两种成分聚集的情况。这些发现具有深远影响，因此迫切需要对该人群采取一级和二级干预措施。
