Damiri Basma, Aghbar Amir, Alkhdour Saja, Arafat Yousef
Faculty of Medicine and Health Science, Drugs and Toxicology Division - An-Najah National University, Palestine.
Faculty of Medicine and Health Science - An-Najah National University, Palestine.
Diabetes Metab Syndr. 2018 May;12(3):343-348. doi: 10.1016/j.dsx.2017.12.021. Epub 2017 Dec 30.
Metabolic Syndrome "MetS" is characterized by the presence of several factors that play a major role in the development of cardiovascular diseases and diabetes mellitus. This study was conducted to establish the prevalence of MetS and its individual components among the overweight and obese students at An-Najah National University (ANU) using IDF and modified NCEP ATP III definition and to identify conditions associated with it.
A cross-sectional study was conducted in 2016. Data were collected in two stages: first stage included anthropometric and blood pressure measurements for 850 participants. Second stage included a self-administered questionnaire and biochemical analysis for only overweight or obese (154) participants.
The prevalence of overweight and obesity was 26.2%, with significant increase among males (36.4%) compared with females (19.1%). The prevalence of MetS among obese and overweight was (28.6%) according to IDF with no significant increase compared to NCEP ATP criteria (24%). Reduced HDL- cholesterol was the most prevalent component (74.7%) in obese and overweight participants followed by central obesity (72.1%), raised blood pressure (29.9%), elevated fasting blood sugar (24%), and lastly increased triglycerides (18.2%). No significant differences were found between males and females according to both criteria. Moreover, no significant associations with geographic locality, house-hold income, smoking, physical activity, or family history were determined.
The prevalence of MetS among overweight and obese young adult Palestinians was high and demands immediate intervention, given the potential for these adults to develop chronic diseases.
代谢综合征(MetS)的特征是存在多种在心血管疾病和糖尿病发展中起主要作用的因素。本研究旨在使用国际糖尿病联盟(IDF)和修改后的美国国家胆固醇教育计划成人治疗小组第三次报告(NCEP ATP III)定义,确定纳贾赫国立大学(ANU)超重和肥胖学生中代谢综合征及其各个组成部分的患病率,并确定与之相关的情况。
2016年进行了一项横断面研究。数据收集分两个阶段进行:第一阶段包括对850名参与者进行人体测量和血压测量。第二阶段仅对超重或肥胖(154名)参与者进行自填式问卷调查和生化分析。
超重和肥胖的患病率为26.2%,男性(36.4%)显著高于女性(19.1%)。根据IDF,肥胖和超重者中代谢综合征的患病率为28.6%,与NCEP ATP标准(24%)相比无显著增加。高密度脂蛋白胆固醇降低是肥胖和超重参与者中最普遍的组成部分(74.7%),其次是中心性肥胖(72.1%)、血压升高(29.9%)、空腹血糖升高(24%),最后是甘油三酯升高(18.2%)。根据这两个标准,男性和女性之间未发现显著差异。此外,未确定与地理位置、家庭收入、吸烟、身体活动或家族史有显著关联。
鉴于这些巴勒斯坦年轻成年人有患慢性病的可能性,超重和肥胖的巴勒斯坦年轻成年人中代谢综合征的患病率很高,需要立即进行干预。