自体脂肪移植即刻重建：对乳腺癌局部复发的影响
Immediate reconstruction with autologous fat grafting: influence in breast cancerregional recurrence.
作者信息
Stumpf Camile Cesa, Biazus Jorge Villanova, Zucatto Fernando Schuh Ângela Erguy, Cericatto Rodrigo, Cavalheiro José Antônio Crespo, Damin Andrea Pires Souto, Melo Márcia Portela
机构信息
- Clinics Hospital of Porto Alegre, Breast Unit, Porto Alegre, Rio Grande do Sul State, Brazil.
出版信息
Rev Col Bras Cir. 2017 Mar-Apr;44(2):179-186. doi: 10.1590/0100-69912017002012.
OBJECTIVE
to evaluate local and systemic recurrence of breast cancer in patients submitted to autologous fat grafting in the immediate reconstruction after conservative surgery for breast cancer.
METHODS
this is a historical cohort study comparing 167 patients submitted to conservative surgery without reconstruction (conservative surgery group) with 27 patients submitted to conservative treatment with immediate graft reconstruction, following the Coleman's technique (lipofilling group). All patients had invasive carcinoma and were operated by a single surgeon from 2004 to 2011. The postoperative follow-up time was 36 months.
RESULTS
the overall incidence of local recurrence was 2.4%. No patient in the lipofilling group had local recurrence during the study period. For systemic recurrence, the rates obtained were 3.7% (one patient) for the fat grafting group and 1.8% (three patients) for the conservative surgery group without reconstruction.
CONCLUSION
there was no significant difference for local or systemic recurrence in the groups studied. Immediate autologous fat grafting appears to be a safe procedure.
目的
评估在乳腺癌保乳手术后即刻进行自体脂肪移植重建的患者中乳腺癌局部和全身复发情况。
方法
这是一项历史性队列研究，将167例接受保乳手术但未进行重建的患者（保乳手术组）与27例采用科尔曼技术（脂肪填充组）进行即刻移植重建的保乳治疗患者进行比较。所有患者均患有浸润性癌，且在2004年至2011年期间由同一位外科医生进行手术。术后随访时间为36个月。
结果
局部复发的总体发生率为2.4%。在研究期间，脂肪填充组无患者发生局部复发。对于全身复发，脂肪移植组的发生率为3.7%（1例患者），未进行重建的保乳手术组为1.8%（3例患者）。
结论
在所研究的组中，局部或全身复发无显著差异。即刻自体脂肪移植似乎是一种安全的手术方法。
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