Araújo Valdelaine Etelvina Miranda de, Bezerra Juliana Maria Trindade, Amâncio Frederico Figueiredo, Passos Valéria Maria de Azeredo, Carneiro Mariângela
Secretaria de Vigilância em Saúde, Ministério da Saúde - Brasília (DF), Brasil.
Epidemiologia das Doenças Infecciosas e Parasitárias, Departamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais - Belo Horizonte (MG), Brasil.
Rev Bras Epidemiol. 2017 May;20Suppl 01(Suppl 01):205-216. doi: 10.1590/1980-5497201700050017.
: To describe the main metrics on dengue generated by Global Burden of Disease (GBD) Study 2015, for Brazil and its 27 federated units, in the years 2000 and 2015.
: The metrics described were: incidence and mortality rates by dengue, standardized by age, years of life lost (YLL), years lived with disability (YLD), and disability-adjusted life years (DALY) (in absolute frequency and age-standardized rates). The estimated metrics were presented with uncertainty intervals (UI 95%) for the years 2000 and 2015, accompanied by the relative percentages of changes.
: The number of cases increased 232.7% and the number of deaths increased 639.0% between 2000 and 2015 in the country. The incidence rate varied 184.3% and the mortality rate was low, but with an increase of 500.0% in the period evaluated. The YLL, YLD, and DALY rates increased 420.0, 187.2, and 266.1%, respectively. In 2015, DALY was similar among women and men (21.9/100,000). The DALY increased more than double in all the Brazilian federated units.
: The marked increase in dengue over the years is associated with the introduction and/or circulation of one or more serotypes of the transmitter virus and an increasing proportion of patients affected by the severe form of the disease. Despite the low mortality rate of the disease in comparison between the years of study, the disease contributes to the loss of healthy years of life in Brazil as it affects a large number of people, from all age groups, causing some degree of disability during the infection and deaths, especially, in children.
描述2015年全球疾病负担（GBD）研究针对巴西及其27个联邦单位在2000年和2015年所生成的登革热主要指标。
所描述的指标包括：按年龄标准化的登革热发病率和死亡率、寿命损失年数（YLL）、带病生存年数（YLD）以及伤残调整生命年（DALY）（以绝对频数和年龄标准化率表示）。所估计的指标呈现了2000年和2015年的不确定性区间（UI 95%），并伴有变化的相对百分比。
该国在2000年至2015年间病例数增加了232.7%，死亡数增加了639.0%。发病率变化了184.3%，死亡率较低，但在所评估期间增加了500.0%。YLL、YLD和DALY率分别增加了420.0%、187.2%和266.1%。2015年，男性和女性的DALY相似（21.9/10万）。所有巴西联邦单位的DALY增加了一倍多。
多年来登革热的显著增加与传播病毒的一种或多种血清型的引入和/或传播以及受该疾病严重形式影响的患者比例增加有关。尽管在所研究年份之间该疾病的死亡率较低，但由于它影响了来自所有年龄组的大量人群，在感染期间导致一定程度的残疾并造成死亡，尤其是儿童死亡，所以该疾病导致了巴西健康生命年的损失。
