Tokue A, Yonese Y, Mato M, Ookawara S
Virchows Arch B Cell Pathol Incl Mol Pathol. 1985;49(3):261-7. doi: 10.1007/BF02912103.
Characteristic intracytoplasmic lamellar bodies were found in a malignant gonadal stromal tumor. These bodies consisted of the stacks of up to 200 tubular cisternae arranged in parallel. Each cisterna had a circular section in tangential view and a diameter of about 85 nm. The cisternae on the outermost side of these lamellar bodies tended to be dilated and adorned with ribosomes. The ends of cisternae were often contiguous with rough-surfaced endoplasmic reticulum. The latter feature is also seen in annulate lamellae, but periodically spaced annuli or discontinuities characteristic of annulate lamellae were never observed. Furthermore, fine ribosomal granules resembling a rosary were recognizable along the whole circumference of the outer surface of each cisterna. The unique structure we describe is a cytoplasmic organelle which, like annulate lamellae, is closely associated with the endoplasmic reticulum and is presumed to be related to the genesis of rough-surfaced endoplasmic reticulum in tumor cells.
在一例恶性性腺间质肿瘤中发现了特征性的胞质内板层小体。这些小体由多达200个平行排列的管状潴泡堆叠而成。每个潴泡在切线方向上呈圆形截面，直径约85nm。这些板层小体最外侧的潴泡往往会扩张并附着有核糖体。潴泡的末端常常与糙面内质网相连。后者这一特征在环状片层中也可见到，但从未观察到环状片层特有的周期性间隔的环或间断。此外，沿着每个潴泡外表面的整个圆周都可辨认出类似念珠的细小核糖体颗粒。我们所描述的这种独特结构是一种细胞质细胞器，它与环状片层一样，与内质网密切相关，并推测与肿瘤细胞中糙面内质网的发生有关。
