University of Brasília, Brasília, Brazil.
Caries Res. 2017;51(4):419-424. doi: 10.1159/000477099. Epub 2017 Jun 29.
The aim of this study was to compare the caries experience of children with and without molar-incisor hypomineralisation (MIH).
A case-control study was designed in which 130 children aged between 7 and 13 years with MIH (cases) were matched with 130 children without the condition (controls) according to age, sex, and school. Dental caries and MIH were assessed using the Caries Assessment Spectrum and Treatment (CAST) and European Academy of Paediatric Dentistry (EAPD) criteria, respectively, by three examiners. CAST was converted into DMFT/dmft; the Kruskal-Wallis test was performed to analyse whether dmft/DMFT was influenced by the severity of MIH. Associations between MIH and dental caries were analysed at child and tooth levels: between and within subjects, respectively. To correlate MIH severity and the occurrence of dental caries, the Cochran-Armitage test was used.
The mean age of the children was 9.63 ± 1.29 years. The mean dmft for cases was 1.23 ± 1.99 and for controls 1.71 ± 2.22 (p > 0.05). For the DMFT, the mean scores for cases and controls were 0.45 ± 0.90 and 0.07 ± 0.25, respectively (p < 0.001). The between-subject analysis showed no difference in relation to enamel carious lesions; however, the prevalence of dentine carious lesions was significantly higher in children with MIH than in those without the condition. The same pattern was seen for the within-subject analysis. It was observed that the increase in MIH severity resulted in more teeth being affected by dentine carious lesions (p = 0.0003).
Children with MIH presented a higher experience of caries in the permanent dentition than those without the condition. MIH was considered a risk factor for caries development.
本研究旨在比较患有和不患有低矿化磨牙（MIH）的儿童的龋齿经历。
设计了一项病例对照研究，其中 130 名年龄在 7 至 13 岁之间患有 MIH（病例）的儿童与 130 名无该病症的儿童（对照）按照年龄、性别和学校进行匹配。使用龋病评估谱和治疗（CAST）和欧洲儿科学会（EAPD）标准分别由三名检查者评估龋齿和 MIH。将 CAST 转换为 DMFT/dmft；采用 Kruskal-Wallis 检验分析 dmft/DMFT 是否受 MIH 严重程度的影响。在儿童和牙齿水平上分析 MIH 与龋齿之间的关系：分别在个体之间和个体内部。为了关联 MIH 严重程度和龋齿的发生，使用 Cochran-Armitage 检验。
儿童的平均年龄为 9.63 ± 1.29 岁。病例的平均 dmft 为 1.23 ± 1.99，对照组为 1.71 ± 2.22（p > 0.05）。对于 DMFT，病例和对照组的平均分数分别为 0.45 ± 0.90 和 0.07 ± 0.25（p < 0.001）。在个体间分析中，釉质龋损方面无差异；然而，患有 MIH 的儿童的牙本质龋损患病率明显高于无该病症的儿童。个体内分析也呈现出相同的模式。观察到 MIH 严重程度的增加导致更多的牙齿受到牙本质龋损的影响（p = 0.0003）。
患有 MIH 的儿童的恒牙龋齿经历高于无该病症的儿童。MIH 被认为是龋齿发生的危险因素。
