Department of Operative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.
Klinik für Zahnerhaltung und Parodontologie, Klinikum der Ludwig-Maximilians-Universität München, Goethestraße 70, 80336, Munich, Germany.
Clin Oral Investig. 2018 Jun;22(5):2013-2019. doi: 10.1007/s00784-017-2299-4. Epub 2017 Dec 9.
This cross-sectional study compared the caries experience in 15-year-olds with and without demarcated hypomineralised lesions (DHL) in permanent teeth.
One thousand three hundred and two 15-year-old adolescents from two ongoing birth cohorts (GINIplus15 and LISAplus15) were examined to determine non-cavitated carious lesions (NCCL) and the DMF index. Furthermore, DHL was scored on all permanent teeth/surfaces according to the molar-incisor hypomineralisation criteria of the European Academy of Paediatric Dentistry (MIH/EAPD). Adolescents with DHL were categorised into those with a minimum of one DHL in the permanent dentition (DHL ≥ 1), with DHL on at least one first permanent molar (MIH/EAPD) and with DHL on at least one first permanent molar and permanent incisor (MIH/Severe). The study was conducted in the metropolitan area of Munich.
The proportion of children without caries amounted to 63.7% (DMF > 0) and 26.0% (DMF > 0); the caries experience was mean = 4.0(SD = 5.2) NCCL/T and 0.9(1.7) DMF/T. Existence of DHL ≥ 1, MIH/EAPD and MIH/Severe was detected in 40.2, 17.2 and 9.8% of all adolescents, respectively. The corresponding DMF/T values were: no DHL 0.9(1.7); DHL ≥ 1 1.0(1.7); MIH/EAPD 1.1(1.6); MIH/Severe 1.1(1.7). The group of adolescents with MIH/EAPD and MIH/Severe were found to have statistically higher caries rates in comparison to those with no DHL.
Caries and DHL are prevalent and influenced the dental health of 15-year-old adolescents. A significant positive association existed between the presence of caries and DHL.
Children with MIH/EAPD or MIH/Severe had a higher probability to develop carious lesions in the permanent dentition.
本横断面研究比较了恒牙中有和无界限性牙釉质发育不全（DHL）病变的 15 岁青少年的龋齿发病情况。
对来自两个正在进行的出生队列（GINIplus15 和 LISAplus15）的 1302 名 15 岁青少年进行了检查，以确定非龋性龋损（NCCL）和 DMF 指数。此外，根据欧洲儿童牙科学会的磨牙-切牙低矿化（MIH/EAPD）标准，对所有恒牙/表面的 DHL 进行了评分。将恒牙中有至少一个 DHL（DHL≥1）、至少一个第一恒磨牙有 DHL（MIH/EAPD）和至少一个第一恒磨牙和恒切牙有 DHL（MIH/Severe）的青少年分为 DHL 组。该研究在慕尼黑大都市区进行。
无龋的儿童比例为 63.7%（DMF＞0）和 26.0%（DMF＞0）；龋齿发病情况为平均 NCCL/T=4.0(SD=5.2)和 0.9(1.7) DMF/T。在所有青少年中，分别有 40.2%、17.2%和 9.8%存在 DHL≥1、MIH/EAPD 和 MIH/Severe。相应的 DMF/T 值分别为：无 DHL 0.9(1.7)；DHL≥1 1.0(1.7)；MIH/EAPD 1.1(1.6)；MIH/Severe 1.1(1.7)。与无 DHL 的青少年相比，MIH/EAPD 和 MIH/Severe 组的青少年龋齿发生率更高，统计学上有显著差异。
龋齿和 DHL 在 15 岁青少年中普遍存在，影响其口腔健康。龋齿的发生与 DHL 之间存在显著的正相关关系。
患有 MIH/EAPD 或 MIH/Severe 的儿童在恒牙中发生龋齿的可能性更高。
