Malone M J, Silverman M L, Braasch J W, Jin G L, Dayal Y
Arch Surg. 1985 Dec;120(12):1381-3. doi: 10.1001/archsurg.1985.01390360047011.
We studied a patient with a very small somatostatinoma that arose from the prominence of the orifice of the duct of Santorini. The patient presented clinically with epigastric discomfort, marked loss of weight, diarrhea, exertional dyspnea, and chest pain. He flushed intermittently and had occasional tachycardia and hypertension. Levels of serum serotonin and urinary 5-hydroxyindoleacetic acid were normal. A small ampullary tumor was resected and identified by immunohistochemical staining to be a somatostatinoma. The patient had gained 6.75 kg and was essentially free of symptoms 16 months after surgery.
我们研究了一名患有极小生长抑素瘤的患者，该肿瘤起源于Santorini导管开口处的隆起。患者临床表现为上腹部不适、明显体重减轻、腹泻、劳力性呼吸困难和胸痛。他间歇性脸红，偶尔出现心动过速和高血压。血清5-羟色胺和尿5-羟吲哚乙酸水平正常。一个小的壶腹肿瘤被切除，经免疫组化染色鉴定为生长抑素瘤。术后16个月，患者体重增加了6.75千克，基本无症状。
