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结直肠癌:术后随访与监测

Colorectal Cancer: Postoperative Follow-up and Surveillance.

作者信息

Godhi Satyajit, Godhi Ashok, Bhat Ravishankar, Saluja Sundeep

机构信息

Surgical Gastroenterology, Apollo Hospitals, Bangalore, Karnataka India.

Surgery, Jawaharlal Nehru Medical College, Belgaum, Karnataka India.

出版信息

Indian J Surg. 2017 Jun;79(3):234-237. doi: 10.1007/s12262-017-1610-6. Epub 2017 Mar 10.

DOI:10.1007/s12262-017-1610-6
PMID:28659677
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5473799/
Abstract

Follow-up and surveillance form an important aspect of care in patients with colorectal cancers (CRC). Most recurrences will occur within 2 years of surgery and 90% by 5 years. Follow up protocols have not been well defined in stage I disease and the approach should be individualized. As 40% of patients with stages II and III will develop recurrences, intensive postoperative follow-up strategy is recommended for them. It includes visit to the clinician for clinical examination, serum carcinoembryonic antigen (CEA), computed tomography (CT) of the chest and abdomen, colonoscopy, and flexible proctosigmoidoscopy in rectal cancers. Surveillance should be undertaken in those who are medically fit for repeat surgical procedures or for chemoradiotherapy. The concept of intensive post operative surveillance is based on the fact that some of these patients can have resectable/curable recurrence.

摘要

随访和监测是结直肠癌(CRC)患者护理的重要方面。大多数复发将发生在手术后2年内,5年内复发率达90%。I期疾病的随访方案尚未明确界定,应采取个体化方法。由于40%的II期和III期患者会出现复发,因此建议对他们采取强化术后随访策略。这包括就诊临床医生进行临床检查、检测血清癌胚抗原(CEA)、进行胸部和腹部计算机断层扫描(CT)、结肠镜检查以及直肠癌的乙状结肠镜检查。对于身体状况适合再次手术或放化疗的患者应进行监测。强化术后监测的理念基于这样一个事实,即这些患者中的一些人可能会出现可切除/可治愈的复发。

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本文引用的文献

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Digestion. 2015;91(2):142-9. doi: 10.1159/000370308. Epub 2015 Feb 10.
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Intensive follow-up strategies improve outcomes in nonmetastatic colorectal cancer patients after curative surgery: a systematic review and meta-analysis.强化随访策略可改善根治性手术后非转移性结直肠癌患者的结局:一项系统评价和荟萃分析。
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Effect of 3 to 5 years of scheduled CEA and CT follow-up to detect recurrence of colorectal cancer: the FACS randomized clinical trial.3 至 5 年定期 CEA 和 CT 随访检测结直肠癌复发的效果:FACS 随机临床试验。
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The role of postoperative colonoscopic surveillance after radical surgery for colorectal cancer: a prospective, randomized clinical study.结直肠癌根治术后结肠镜监测的作用:一项前瞻性随机临床研究。
Gastrointest Endosc. 2009 Mar;69(3 Pt 2):609-15. doi: 10.1016/j.gie.2008.05.017. Epub 2009 Jan 10.
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Follow-up after curative resection of colorectal cancer: a meta-analysis.结直肠癌根治性切除术后的随访:一项荟萃分析。
Dis Colon Rectum. 2007 Nov;50(11):1783-99. doi: 10.1007/s10350-007-9030-5.
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