Maletta G J
Geriatrics. 1985 Dec;40(12):31-6, 39-40, 42.
Benzodiazepines are used often in elderly, anxious patients with or without dementia. Clearly efficacious and relatively safe, benzodiazepines should be considered the first-line drugs of choice to treat anxiety associated with Alzheimer's disease. "Second-generation" antidepressants, although considerably more expensive than the tricyclics, are of significant benefit in the elderly, primarily because of extremely low anticholinergic side effects.
苯二氮䓬类药物常用于患有或未患有痴呆症的老年焦虑患者。苯二氮䓬类药物疗效确切且相对安全,应被视为治疗与阿尔茨海默病相关焦虑症的一线首选药物。“第二代”抗抑郁药虽然比三环类药物贵得多,但对老年人有显著益处,主要是因为其抗胆碱能副作用极低。